Discuss This Drug

Natamycin

CHEBI:CHEBI_7488

Definition

A macrolide antibiotic that has formula C33H47NO13, produced by several Streptomyces species including Streptomyces natalensis. It exhibits broad spectrum antifungal activity and used in eye drops, and as a food preservative, and also as a postharvest biofungicide for citrus and other fruit crops.

Chemical Information

Molecular Formula
C33H47NO13
Molecular Mass
665.733
Charge
0
SMILES
[H][C@@]12C[C@H](O)C[C@]3(O)C[C@H](O)[C@@H](C(O)=O)[C@]([H])(C[C@@H](O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O)\C=C\C=C\C=C\C=C\C[C@@H](C)OC(=O)\C=C\[C@H]1O2)O3
InChI
InChI=1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32+,33-/m1/s1
InChIKey
NCXMLFZGDNKEPB-FFPOYIOWSA-N

Alternative Names

  • antibiotic A-5283
  • CL 12,625
  • CL 12625
  • Delvocid
  • Delvolan
  • Delvopos
  • E 235
  • E-235
  • Mycophyt
  • Myprozine
  • Myuprozine
  • Natacyn
  • Natajen
  • Natamatrix
  • Natamax
  • natamicina
  • natamycin
  • natamycine
  • natamycinum
  • Pimafucin
  • pimaricin
  • pimaricine
  • Pimarizin
  • Synogil
  • tennecetin
  • (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0(5,7)]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
7268
oboInOwl#hasDbXref
Wikipedia:Natamycin
core#notation
CHEBI:7488

Additional References

Wikipedia:Natamycin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
7268
oboInOwl#hasDbXref
Wikipedia:Natamycin
oboInOwl#id
CHEBI:7488
generic_name
natamycin
product_type
HUMAN PRESCRIPTION DRUG
marketing_category
NDA
listing_expiration_date
20251231
route
OPHTHALMIC
marketing_start_date
20210612
package_marketing_start_date
20210612
dosage_form
SUSPENSION/ DROPS
labeler_name
Eyevance Pharmaceuticals, LLC
brand_name
NATACYN
brand_name_base
NATACYN
product_ndc
71776-005
application_number
NDA050514
spl_id
236ef567-97be-29bd-e063-6394a90ad47f
package_ndc
71776-005-15
package_description
1 BOTTLE, GLASS in 1 CARTON (71776-005-15) / 15 mL in 1 BOTTLE, GLASS
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_65256
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:7488
rxcui
207100
nui
N0000175936
pharm_class
Polyene Antimicrobial [EPC]
pharm_class_cs
Polyenes [CS]
active_ingredient_strength
50 mg/mL
manufacturer_name
Eyevance Pharmaceuticals, LLC
active_ingredient_name
NATAMYCIN
unii
8O0C852CPO
spl_set_id
2818fcb8-5bac-41fb-864e-3b598308a428
pharm_class_epc
Polyene Antimicrobial [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_1248
owl#annotatedSource
t283735
owl#someValuesFrom
t3010543