Neostigmine
CHEBI:CHEBI_7514
Definition
A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Chemical Information
- Molecular Formula
- C12H19N2O2
- Molecular Mass
- 223.29150
- Charge
- +1
- SMILES
- CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C
- InChI
- InChI=1S/C12H19N2O2/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5/h6-9H,1-5H3/q+1
- InChIKey
- ALWKGYPQUAPLQC-UHFFFAOYSA-N
Alternative Names
- (m-Hydroxyphenyl)trimethylammonium dimethylcarbamate
- 3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium
- 3-Trimethylammoniumphenyl N,N-dimethylcarbamate
- Eustigmin
- Eustigmine
- m-Trimethylammoniumphenyldimethylcarbamate
- Prostigmine
- Vagostigmine
Drug Classification
-
quaternary ammonium ionView Class →
CHEBI:35267
-
t286005
-
t286254
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 7315
- oboInOwl#hasDbXref
- Wikipedia:Neostigmine
- core#notation
- CHEBI:7514
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- dosage_form
- INJECTION, SOLUTION
- marketing_start_date
- 20110719
- labeler_name
- Endo USA
- application_number
- ANDA209135
- product_ndc
- 76045-214
- rxcui
- 2673236
- package_marketing_start_date
- 15-JUN-18
- manufacturer_name
- Endo USA
- unii
- 98IMH7M386
- spl_set_id
- 7978e3c0-6ee3-6db5-e053-2991aa0a2d33
- package_description
- 10 VIAL, MULTI-DOSE in 1 TRAY (63323-413-10) / 10 mL in 1 VIAL, MULTI-DOSE (63323-413-01)
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 7315
- oboInOwl#hasDbXref
- Wikipedia:Neostigmine
- oboInOwl#id
- CHEBI:7514
- generic_name
- neostigmine methylsulfate and glycopyrrolate
- brand_name
- Bloxiverz
- brand_name_base
- Bloxiverz
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_74530
- core#notation
- CHEBI:7514
- pharm_class
- Cholinesterase Inhibitors [MoA]
- active_ingredient_name
- NEOSTIGMINE METHYLSULFATE
- active_ingredient_strength
- .51 mg/mL
- upc
- 0365219811015
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- listing_expiration_date
- 20241231
- route
- INTRAVENOUS
- spl_id
- a2bf3680-0b67-4548-885a-be7a6aaaf89e
- package_ndc
- 14593-903-05
- has_treatment
- http://purl.obolibrary.org/obo/DOID_8440
- owl#annotatedSource
- t286900
- owl#someValuesFrom
- t3970136