Discuss This Drug

Nicardipine

CHEBI:CHEBI_7550

Definition

A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.

Chemical Information

Molecular Formula
C26H29N3O6
Molecular Mass
479.533
Charge
0

Alternative Names

  • (+-)-nicardipine
  • (RS)-nicardipine
  • 2-[benzyl(methyl)amino]ethyl methyl (4RS)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • nicardipine
  • nicardipineum
  • nicardipino
  • perpidine
  • rac-nicardipine
  • racemic nicardipine
  • YC-93 free base

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Nicardipine
DRON_00010000
7396
core#notation
CHEBI:7550

Additional References

Wikipedia:Nicardipine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
INTRAVENOUS
spl_id
a935edd9-4154-42a4-b769-0824200959e7
package_ndc
72485-116-10
package_description
10 VIAL in 1 CARTON (72485-116-10) / 10 mL in 1 VIAL (72485-116-01)
marketing_start_date
20100505
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION
labeler_name
Chengdu Shuode Pharmaceutical Co., Ltd
application_number
ANDA211121
product_ndc
14501-0113
rxcui
858605
manufacturer_name
Chengdu Shuode Pharmaceutical Co., Ltd
package_marketing_start_date
05-DEC-20
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Nicardipine
DRON_00010000
7396
oboInOwl#id
CHEBI:7550
generic_name
Nicardipine HCl
brand_name
Nicardipine hydrochloride
brand_name_base
Nicardipine hydrochloride
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_88230
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020325
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_180904
core#notation
CHEBI:7550
pharm_class_moa
Cytochrome P450 2C8 Inhibitors [MoA]
pharm_class
Cytochrome P450 2C8 Inhibitors [MoA]
nui
N0000187062
active_ingredient_strength
25 mg/10mL
pharm_class_epc
Dihydropyridine Calcium Channel Blocker [EPC]
pharm_class_cs
Dihydropyridines [CS]
active_ingredient_name
NICARDIPINE
unii
CZ5312222S
spl_set_id
7226a518-164b-4755-9624-1cc75c939063
upc
0372485116010
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_10823
owl#annotatedSource
t287110
owl#someValuesFrom
t2999933