Niclosamide

CHEBI:CHEBI_7553

Definition

A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.

Chemical Information

Molecular Formula
C13H8Cl2N2O4
Molecular Mass
327.120
Charge
0
SMILES
OC1=CC=C(Cl)C=C1C(=O)NC1=C(Cl)C=C(C=C1)[N+]([O-])=O
InChI
InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)
InChIKey
RJMUSRYZPJIFPJ-UHFFFAOYSA-N

Alternative Names

  • 2-chloro-4-nitrophenylamide-6-chlorosalicylic acid
  • 2-hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide
  • 2',5-dichloro-2-hydroxy-4'-nitrobenzanilide
  • 2',5-dichloro-4'-nitrosalicylanilide
  • 5-chloro-2'-chloro-4'-nitrosalicylanilide
  • 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
  • 5-chloro-N-(2'-chloro-4'-nitrophenyl)salicylamide
  • Atenase
  • B 2353
  • BAY 2353
  • Bayer 2353
  • Bayer 73
  • Bayluscide
  • Cestocid
  • clonitralide
  • Devermin
  • Devermine
  • Fedal-Telmin
  • Fenasal
  • Helmiantin
  • HL 2447
  • Iomesan
  • Lintex
  • Mansonil
  • Mato
  • N-(2-chloro-4-nitrophenyl)-5-chlorosalicylamide
  • N-(2'-chloro-4'-nitrophenyl)-5-chlorosalicylamide
  • Nasemo
  • Niclocide
  • niclosamida
  • niclosamide
  • niclosamidum
  • Phenasal
  • Radeverm
  • Sagimid
  • Sulqui
  • Tredemine
  • Utosamide
  • Vermitid
  • Vermitin
  • WR 46234
  • Yomesan
  • Zestocarp

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
7402
oboInOwl#hasDbXref
Wikipedia:Niclosamide
core#notation
CHEBI:7553

Additional References

Wikipedia:Niclosamide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
7402
oboInOwl#hasDbXref
Wikipedia:Niclosamide
oboInOwl#id
CHEBI:7553
oboInOwl#hasAlternativeId
CHEBI:92630
generic_name
Niclosamide micronized
product_ndc
59349-0033
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35443
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_420128
core#notation
CHEBI:7553
listing_expiration_date
20241231
dosage_form
POWDER
marketing_start_date
20081229
active_ingredient_strength
1 kg/kg
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
labeler_name
Derivados Quimicos SAU
spl_id
f5fcb372-d15d-76de-e053-2995a90a0a76
active_ingredient_name
NICLOSAMIDE
package_ndc
59349-0033-0
package_description
1 BAG in 1 DRUM (59349-0033-0) / 1 BAG in 1 BAG / 25 kg in 1 BAG
package_marketing_start_date
29-DEC-08
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_2929
owl#annotatedSource
t287121
owl#someValuesFrom
t934559