Discuss This Drug

Nisoldipine

CHEBI:CHEBI_7577

Definition

A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.

Alternative Names

  • (+-)-isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate
  • 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-methylpropyl ester
  • Baymycard
  • nisoldipine
  • nisoldipino
  • nisoldipinum
  • rac-methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • Sular
  • Syscor
  • Zadipina

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
7435
oboInOwl#hasDbXref
Wikipedia:Nisoldipine
core#notation
CHEBI:7577

Additional References

Wikipedia:Nisoldipine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
7435
oboInOwl#hasDbXref
Wikipedia:Nisoldipine
oboInOwl#id
CHEBI:7577
generic_name
Nisoldipine
brand_name
Sular
brand_name_base
Sular
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
TABLET, FILM COATED, EXTENDED RELEASE
marketing_start_date
20080725
labeler_name
Covis Pharma US, Inc
product_ndc
0378-2098
application_number
ANDA079051
spl_id
16ac82a9-fd45-484e-b424-52c33aa6e703
package_ndc
0378-2098-01
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38215
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BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020325
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_76919
core#notation
CHEBI:7577
rxcui
790840
active_ingredient_strength
25.5 mg/1
pharm_class_pe
Decreased Blood Pressure [PE]
pharm_class
Dihydropyridines [CS]
pharm_class_moa
Calcium Channel Antagonists [MoA]
nui
N0000178477
pharm_class_epc
Dihydropyridine Calcium Channel Blocker [EPC]
pharm_class_cs
Dihydropyridines [CS]
package_marketing_start_date
20080725
manufacturer_name
Covis Pharma US, Inc
active_ingredient_name
NISOLDIPINE
package_description
100 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (0378-2098-01)
unii
4I8HAB65SZ
spl_set_id
8a5fb6a2-9fae-4872-8c5c-0f1ba03a57cb
upc
0303782097016
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
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owl#annotatedSource
t287113
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t3005092