amfenac
CHEBI:CHEBI_75915
Definition
An oxo monocarboxylic acid that is benzophenone in which one of the phenyl groups is substituted by an amino group and a carboxymethyl group at position 2 and 3, respectively. The corresponding carboxamide, nepafenac, is a prodrug of amfenac and is used for the treatment of pain and inflammation following cataract surgery.
Chemical Information
- Molecular Formula
- C15H13NO3
- Molecular Mass
- 255.26860
- Charge
- 0
- SMILES
- Nc1c(CC(O)=O)cccc1C(=O)c1ccccc1
- InChI
- InChI=1S/C15H13NO3/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10/h1-8H,9,16H2,(H,17,18)
- InChIKey
- SOYCMDCMZDHQFP-UHFFFAOYSA-N
Alternative Names
- (2-amino-3-benzoylphenyl)acetic acid
- (2-Amino-3-benzoylphenyl)essigsaeure
- 2-amino-3-benzoylbenzeneacetic acid
- amfenac
- amfenaco
- amfenacum
Treatment Applications
-
cataract 29View Disease →
DOID:0110232
-
cataract 42View Disease →
DOID:0110237
Drug Classification
-
substituted anilineView Class →
CHEBI:48975
-
benzophenonesView Class →
CHEBI:22726
-
primary amino compoundView Class →
CHEBI:50994
-
amino acidView Class →
CHEBI:33709
-
Amino AcidsView Class →
CHEBI:33709
-
oxo monocarboxylic acidView Class →
CHEBI:35871
-
t286049
-
t286224
-
t286716
-
t286734
-
t286837
-
t286939
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Amfenac
- core#notation
- CHEBI:75915
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Amfenac
- oboInOwl#id
- CHEBI:75915
- core#notation
- CHEBI:75915
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50630
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_75917
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_104591
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_240107
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect13603
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_75917
- owl#someValuesFrom
- t286389
- owl#annotatedSource
- t287057