Discuss This Drug

nepafenac

CHEBI:CHEBI_75922

Definition

A monocarboxylic acid amide that is amfenac in which the carboxylic acid group has been converted into the corresponding carboxamide. It is a prodrug for amfenac, used in eye drops to treat pain and inflammation following cataract surgery.

Chemical Information

Molecular Formula
C15H14N2O2
Molecular Mass
254.28390
Charge
0
SMILES
NC(=O)Cc1cccc(C(=O)c2ccccc2)c1N
InChI
InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)
InChIKey
QEFAQIPZVLVERP-UHFFFAOYSA-N

Alternative Names

  • 2-(2-amino-3-benzoylphenyl)acetamide
  • 2-amino-3-benzoylbenzeneacetamide
  • AHR 9434
  • AHR-9434
  • AL 6515
  • AL-6515
  • nepafenac
  • nepafenaco
  • nepafenacum
  • Nevanac

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:75922
DRON_00010000
298665
oboInOwl#hasDbXref
Wikipedia:Nepafenac

Additional References

Wikipedia:Nepafenac

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:75922
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
298665
oboInOwl#hasDbXref
Wikipedia:Nepafenac
oboInOwl#id
CHEBI:75922
generic_name
Nepafenac Sterile
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
SUSPENSION/ DROPS
marketing_start_date
20050819
labeler_name
Nanjing Chemlin Biomedical Science & Technology Co, Ltd.
product_ndc
64181-0019
brand_name
NEVANAC
brand_name_base
NEVANAC
application_number
NDA021862
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50630
rxcui
1365866
pharm_class
Non-Steroidal [CS]
listing_expiration_date
20241231
nui
N0000175722
pharm_class_epc
Nonsteroidal Anti-inflammatory Drug [EPC]
pharm_class_moa
Cyclooxygenase Inhibitors [MoA]
pharm_class_cs
Anti-Inflammatory Agents, Non-Steroidal [CS]
active_ingredient_strength
1.375 kg/1.375kg
package_marketing_start_date
01-FEB-09
route
OPHTHALMIC
manufacturer_name
Novartis Pharmaceuticals Corporation
spl_id
1c6d059d-fa93-29b5-e063-6394a90a41e0
active_ingredient_name
NEPAFENAC
package_ndc
64181-0019-0
package_description
6 kg in 1 DRUM (64181-0019-0)
unii
0J9L7J6V8C
spl_set_id
a2909252-c5f1-421f-9073-b7be90b45b51
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_4447
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect34444
owl#annotatedSource
t287089
owl#someValuesFrom
t612636