dimethyl fumarate

CHEBI:CHEBI_76004

Definition

An enoate ester resulting from the formal condensation of both carboxy groups of fumaric acid with methanol. Used for treatment of adults with relapsing forms of multiple sclerosis.

Chemical Information

Molecular Formula: C6H8O4
Molecular Mass: 144.12530
Charge: 0
SMILES: COC(=O)\C=C\C(=O)OC
InChI: InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+
InChIKey: LDCRTTXIJACKKU-ONEGZZNKSA-N

Alternative Names

(E)-But-2-enedioic acid dimethyl ester
1,2-bis(methoxycarbonyl)-trans-ethylene
dimethyl (2E)-but-2-enedioate
Dimethyl trans-ethylenedicarboxylate
Fumaric acid, dimethyl ester
Tecfidera
trans-1,2-Ethylenedicarboxylic acid dimethyl ester
trans-Butenedioic acid dimethyl ester

Treatment Applications

Balo concentric sclerosis
DOID:0060215

View Disease →
multiple sclerosis
DOID:2377

View Disease →
obsolete chronic progressive multiple sclerosis
DOID:2376

View Disease →
relapsing-remitting multiple sclerosis
DOID:2378

View Disease →

Drug Classification

methyl ester
CHEBI:25248

View Class →
diester
CHEBI:51307

View Class →
enoate ester
CHEBI:51702

View Class →
t285822
t286348
t286538

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

Always consult with a healthcare professional before starting, stopping, or modifying any medication.
Side effects may vary and this list may not be comprehensive.
Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000: 1373478
oboInOwl#hasDbXref: Wikipedia:Dimethyl_fumarate
core#notation: CHEBI:76004

Additional References

Wikipedia:Dimethyl_fumarate

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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DRON_00010000: 1373478
oboInOwl#hasDbXref: Wikipedia:Dimethyl_fumarate
oboInOwl#id: CHEBI:76004
core#notation: CHEBI:76004
RO_0000087: http://purl.obolibrary.org/obo/CHEBI_50748
oboInOwl#inSubset: http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent: http://purl.obolibrary.org/obo/CHEBI_18012
22-rdf-syntax-ns#type: http://www.w3.org/2002/07/owl#Class
rdf-schema#range: https://w3id.org/def/predibionto#has_drug_109735
has_treatment: http://purl.obolibrary.org/obo/DOID_638
rdf-schema#domain: https://w3id.org/def/predibionto#has_side_effect34504
owl#annotatedSource: t287027
owl#someValuesFrom: t2992748