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Oxyphenbutazone

CHEBI:CHEBI_76258

Definition

A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Chemical Information

Molecular Formula
C19H20N2O3
Molecular Mass
324.37370
Charge
0
SMILES
CCCCC1C(=O)N(N(C1=O)c1ccc(O)cc1)c1ccccc1
InChI
InChI=1S/C19H20N2O3/c1-2-3-9-17-18(23)20(14-7-5-4-6-8-14)21(19(17)24)15-10-12-16(22)13-11-15/h4-8,10-13,17,22H,2-3,9H2,1H3
InChIKey
HFHZKZSRXITVMK-UHFFFAOYSA-N

Alternative Names

  • 1-(p-Hydroxyphenyl)-2-phenyl-4-butyl-3,5-pyrazolidinedione
  • 1-Phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-butylpyrazolidine
  • 1-Phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-n-butylpyrazolidine
  • 3,5-Dioxo-1-phenyl-2-(p-hydroxyphenyl)-4-N-butylpyrazolidene
  • 4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione
  • 4-Butyl-1-(p-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione
  • 4-Butyl-2-(4-hydroxyphenyl)-1-phenyl-3,5-dioxopyrazolidine
  • 4-Butyl-2-(p-hydroxyphenyl)-1-phenyl-3,5-pyrazolidinedione
  • Hydroxyphenylbutazon
  • Oxi-fenibutol
  • oxifenbutazona
  • Oxifenylbutazon
  • Oxiphenbutazonum
  • oxyphenbutazone
  • oxyphenbutazonum
  • Oxyphenylbutazone
  • p-Hydroxyphenylbutazone
  • p-Oxyphenylbutazone

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Oxyphenbutazone
DRON_00010000
7816
core#notation
CHEBI:76258

Additional References

Wikipedia:Oxyphenbutazone

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Additional Attributes

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