Bromhexine
CHEBI:CHEBI_77032
Definition
A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).
Chemical Information
- Molecular Formula
- C14H20Br2N2
- Molecular Mass
- 376.13000
- Charge
- 0
- SMILES
- CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1
- InChI
- InChI=1S/C14H20Br2N2/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17/h7-8,12H,2-6,9,17H2,1H3
- InChIKey
- OJGDCBLYJGHCIH-UHFFFAOYSA-N
Alternative Names
- 2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline
- 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine
- bromhexina
- bromhexine
- bromhexinum
- Fluibron
- N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine
Treatment Applications
-
primary ciliary dyskinesia 12View Disease →
DOID:0110601
-
pneumonic plagueView Disease →
DOID:10398
-
obsolete parainfluenzal pneumoniaView Disease →
DOID:14475
-
bulbar polioView Disease →
DOID:9786
Drug Classification
-
substituted anilineView Class →
CHEBI:48975
-
tertiary amino compoundView Class →
CHEBI:50996
-
organobromine compoundView Class →
CHEBI:37141
-
t292618
-
t293302
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1753
- oboInOwl#hasDbXref
- Wikipedia:Bromhexine
- core#notation
- CHEBI:77032
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1753
- oboInOwl#hasDbXref
- Wikipedia:Bromhexine
- oboInOwl#id
- CHEBI:77032
- core#notation
- CHEBI:77032
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_77034
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_77040
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113809
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_77040
- owl#annotatedSource
- t293778
- owl#someValuesFrom
- t2915044