Discuss This Drug

Ofloxacin

CHEBI:CHEBI_7731

Definition

A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Chemical Information

Molecular Formula
C18H20FN3O4
Molecular Mass
361.373
Charge
0

Alternative Names

  • (+-)-ofloxacin
  • (3RS)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
  • DL 8280
  • DL-8280
  • Exocin
  • Floxin
  • Gailuoxian
  • HOE 280
  • HOE-280
  • Ocuflox
  • ofloxacin
  • ofloxacine
  • ofloxacino
  • ofloxacinum
  • OFLX
  • ORF 18489
  • Oxaldin
  • Prifloxcin
  • Prifloxin
  • rac-8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
  • rac-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
  • rac-ofloxacin
  • racemic ofloxacin
  • Tarivid
  • Visiren

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Ofloxacin
DRON_00010000
7623
core#notation
CHEBI:7731

Additional References

Wikipedia:Ofloxacin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_63598
listing_expiration_date
20241231
marketing_start_date
20040514
labeler_name
Proficient Rx LP
spl_id
54900137-8062-44cc-9505-3d65dedc8a16
route
OPHTHALMIC
package_ndc
82804-061-05
product_type
HUMAN PRESCRIPTION DRUG
marketing_category
ANDA
dosage_form
TABLET, COATED
application_number
NDA019921
product_ndc
67296-1866
package_marketing_start_date
20150317
package_description
5 mL in 1 BOTTLE, DROPPER (63629-8716-1)
active_ingredient_name
OFLOXACIN
active_ingredient_strength
300 mg/1
nui
M0023650
upc
0382804061051
spl_set_id
cd01954d-918b-456a-e053-2995a90a859c
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Ofloxacin
DRON_00010000
7623
oboInOwl#hasAlternativeId
CHEBI:100146
oboInOwl#id
CHEBI:7731
generic_name
Ofloxacin Ophth Soln
brand_name
OCUFLOX
brand_name_base
OCUFLOX
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_59517
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rxcui
207202
manufacturer_name
NuCare Pharmaceuticaals,Inc.
unii
A4P49JAZ9H
core#notation
CHEBI:7731
pharm_class_epc
Quinolone Antimicrobial [EPC]
pharm_class
Quinolones [CS]
pharm_class_cs
Quinolones [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_4665
owl#annotatedSource
t293862
owl#someValuesFrom
t1027647