ent-crizotinib

CHEBI:CHEBI_77555

Definition

A 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that is the (S)-enantiomer of crizotinib.

Chemical Information

Molecular Formula
C21H22Cl2FN5O
Molecular Mass
450.33700
Charge
0
SMILES
C[C@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl
InChI
InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m0/s1
InChIKey
KTEIFNKAUNYNJU-LBPRGKRZSA-N

Alternative Names

  • (S)-crizotinib

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:77555
oboInOwl#hasDbXref
Reaxys:23379227

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#id
CHEBI:77555
core#notation
CHEBI:77555
oboInOwl#hasDbXref
Reaxys:23379227
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_enantiomer_of
http://purl.obolibrary.org/obo/CHEBI_64310
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#someValuesFrom
t265652
owl#annotatedSource
t293584