Discuss This Drug

armodafinil

CHEBI:CHEBI_77590

Definition

A 2-[(diphenylmethyl)sulfinyl]acetamide that has R configuration at the sulfur atom. Like its racemate, modafinil, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. Peak concentration in the blood later occurs later following administration than with modafinil, so it is thought that armodafinil may be more effective than modafinil in treating people with excessive daytime sleepiness.

Chemical Information

Molecular Formula
C15H15NO2S
Molecular Mass
273.35000
Charge
0
SMILES
NC(=O)C[S@@](=O)C(c1ccccc1)c1ccccc1
InChI
InChI=1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)/t19-/m1/s1
InChIKey
YFGHCGITMMYXAQ-LJQANCHMSA-N

Alternative Names

  • (-)-(R)-modafinil
  • (-)-modafinil
  • (R)-(-)-modafinil
  • (R)-modafinil
  • 2-[(R)-(diphenylmethyl)sulfinyl]acetamide
  • armodafinil
  • armodafinilo
  • armodafinilum
  • CEP 10953
  • CEP-10953
  • Nuvigil

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:77590
oboInOwl#hasDbXref
Wikipedia:Armodafinil
DRON_00010000
641465

Additional References

Wikipedia:Armodafinil

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:77590
rxcui
861962
dea_schedule
CIV
active_ingredient_strength
50 kg/50kg
manufacturer_name
Natco Pharma USA LLC
package_marketing_start_date
20210105
active_ingredient_name
ARMODAFINIL
unii
V63XWA605I
spl_set_id
de2f0921-e791-426c-9192-2b7162e2158c
upc
0369339179031
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
listing_expiration_date
20241231
route
ORAL
labeler_name
Natco Pharma USA LLC
marketing_start_date
20060727
application_number
ANDA202768
spl_id
35852df7-4a3e-4658-9cf8-90b1966adfe4
package_ndc
65129-1185-0
marketing_category
DRUG FOR FURTHER PROCESSING
package_description
45 kg in 1 BAG (65129-1185-0)
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Armodafinil
DRON_00010000
641465
generic_name
ARMODAFINIL
oboInOwl#id
CHEBI:77590
brand_name
ARMODAFINIL
brand_name_base
ARMODAFINIL
product_type
BULK INGREDIENT
dosage_form
POWDER
product_ndc
65129-1185
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77567
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_enantiomer_of
http://purl.obolibrary.org/obo/CHEBI_77591
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_31859
has_treatment
http://purl.obolibrary.org/obo/DOID_0050847
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_104367
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect18155
owl#someValuesFrom
t1024861
owl#annotatedSource
t297250