Oxamniquine
CHEBI:CHEBI_7819
Definition
A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
Chemical Information
- Molecular Formula
- C14H21N3O3
- Molecular Mass
- 279.33480
- Charge
- 0
Alternative Names
- (+-)-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
- (+-)-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
- (+-)-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
- 1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
- 6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
- Mansil
- oxamniquina
- oxamniquine
- oxamniquinum
- rac-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
- rac-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
- rac-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
- rac-oxamniquine
- UK 4271
- UK-4271
- UK4271
- Vansil
Treatment Applications
-
intestinal schistosomiasisView Disease →
DOID:0050597
-
schistosomiasisView Disease →
DOID:1395
-
neuroschistosomiasisView Disease →
DOID:13722
-
urinary schistosomiasisView Disease →
DOID:1394
Drug Classification
-
racemateView Class →
CHEBI:60911
-
t296540
-
t296837
-
t297233
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 7778
- oboInOwl#hasDbXref
- Wikipedia:Oxamniquine
- core#notation
- CHEBI:7819
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 7778
- oboInOwl#hasDbXref
- Wikipedia:Oxamniquine
- oboInOwl#id
- CHEBI:7819
- core#notation
- CHEBI:7819
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_38941
- BFO_0000051
- http://purl.obolibrary.org/obo/CHEBI_78418
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_13720
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_112227
- owl#annotatedSource
- t297265
- owl#someValuesFrom
- t724727