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oxiconazole

CHEBI:CHEBI_7825

Definition

An oxime O-ether that is the 2,4-dichlorobenzyl ether of the oxime obtained by formal condensation of hydroxylamine with the carbonyl group of acetopnenone in which the phenyl group is substituted by chlorines at positions 2 and 4, and in which one of the hydrogens of the methyl group is replaced by a 1H-imidazol-1-yl group. An antifungal agent, it is used (generally as the nitrate salt) in creams and powders for the topical treatment of fungal skin infections.

Chemical Information

Molecular Formula
C18H13Cl4N3O
Molecular Mass
429.12700
Charge
0
SMILES
Clc1ccc(CO\N=C(/Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1
InChI
InChI=1S/C18H13Cl4N3O/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22/h1-8,11H,9-10H2/b24-18+
InChIKey
QRJJEGAJXVEBNE-HKOYGPOVSA-N

Alternative Names

  • (1Z)-N-[(2,4-dichlorobenzyl)oxy]-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanimine
  • 2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-[O-(2,4-dichlorobenzyl)oxime]
  • oxiconazol
  • oxiconazole
  • oxiconazolum
  • Ro 13-8996

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:7825
DRON_00010000
32638
oboInOwl#hasDbXref
Wikipedia:Oxiconazole

Additional References

Wikipedia:Oxiconazole

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:7825
pharm_class
Azoles [CS]
active_ingredient_strength
10 mg/g
upc
0301680358307
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
32638
oboInOwl#hasDbXref
Wikipedia:Oxiconazole
oboInOwl#id
CHEBI:7825
rxcui
312139
product_type
BULK INGREDIENT
listing_expiration_date
20241231
marketing_category
BULK INGREDIENT
dosage_form
CREAM
route
TOPICAL
marketing_start_date
20160307
package_marketing_start_date
20160307
labeler_name
Taro Pharmaceuticals U.S.A., Inc.
generic_name
Oxiconazole Nitrate
active_ingredient_name
OXICONAZOLE
product_ndc
0168-0358
spl_id
ced09ac9-d81c-4812-905e-80abec8141da
package_ndc
0168-0358-90
package_description
90 g in 1 TUBE (0168-0358-90)
manufacturer_name
Taro Pharmaceuticals U.S.A., Inc.
brand_name
Oxiconazole Nitrate
brand_name_base
Oxiconazole Nitrate
application_number
NDA019828
unii
RQ8UL4C17S
spl_set_id
aa368d2b-a5d2-49dd-86e1-5693b68b46f4
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_77698
has_treatment
http://purl.obolibrary.org/obo/DOID_10508
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect34825
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_77698
owl#annotatedSource
t297211
owl#someValuesFrom
t905723