oxiconazole
CHEBI:CHEBI_7825
Definition
An oxime O-ether that is the 2,4-dichlorobenzyl ether of the oxime obtained by formal condensation of hydroxylamine with the carbonyl group of acetopnenone in which the phenyl group is substituted by chlorines at positions 2 and 4, and in which one of the hydrogens of the methyl group is replaced by a 1H-imidazol-1-yl group. An antifungal agent, it is used (generally as the nitrate salt) in creams and powders for the topical treatment of fungal skin infections.
Chemical Information
- Molecular Formula
- C18H13Cl4N3O
- Molecular Mass
- 429.12700
- Charge
- 0
- SMILES
- Clc1ccc(CO\N=C(/Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1
- InChI
- InChI=1S/C18H13Cl4N3O/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22/h1-8,11H,9-10H2/b24-18+
- InChIKey
- QRJJEGAJXVEBNE-HKOYGPOVSA-N
Alternative Names
- (1Z)-N-[(2,4-dichlorobenzyl)oxy]-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanimine
- 2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-[O-(2,4-dichlorobenzyl)oxime]
- oxiconazol
- oxiconazole
- oxiconazolum
- Ro 13-8996
Drug Classification
-
oxime O-etherView Class →
CHEBI:36816
-
conazole antifungal drugView Class →
CHEBI:87071
-
dichlorobenzeneView Class →
CHEBI:23697
-
DichlorobenzeneView Class →
CHEBI:23697
-
imidazole antifungal drugView Class →
CHEBI:87069
-
t296122
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 32638
- oboInOwl#hasDbXref
- Wikipedia:Oxiconazole
- core#notation
- CHEBI:7825
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 32638
- oboInOwl#hasDbXref
- Wikipedia:Oxiconazole
- oboInOwl#id
- CHEBI:7825
- core#notation
- CHEBI:7825
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_77698
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_10508
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect34825
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_77698
- owl#annotatedSource
- t297211
- owl#someValuesFrom
- t905723