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Oxymetazoline

CHEBI:CHEBI_7862

Definition

A member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion.

Chemical Information

Molecular Formula
C16H24N2O
Molecular Mass
260.37460
Charge
0
SMILES
Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C
InChI
InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)
InChIKey
WYWIFABBXFUGLM-UHFFFAOYSA-N

Alternative Names

  • 2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
  • 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
  • 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
  • 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
  • 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
  • oxymetazolina
  • oxymetazoline
  • oxymetazolinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
7812
oboInOwl#hasDbXref
Wikipedia:Oxymetazoline
core#notation
CHEBI:7862

Additional References

Wikipedia:Oxymetazoline

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

dosage_form
SPRAY, METERED
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
application_number
NDA212520
labeler_name
Cardinal Health 110,Inc
product_ndc
69842-715
marketing_start_date
20111028
route
NASAL
package_ndc
55319-716-30
spl_id
d8a1f83d-f756-41bc-a05a-8633e53a62a2
package_description
1 BOTTLE, SPRAY in 1 CARTON (72288-703-10) / 30 mL in 1 BOTTLE, SPRAY
brand_name_base
basic care no drip nasal
brand_name
KROGER No Drip Nasal Mist Severe Congestion
listing_expiration_date
20241231
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
7812
oboInOwl#hasDbXref
Wikipedia:Oxymetazoline
oboInOwl#id
CHEBI:7862
generic_name
Oxymetazoline hydrochloride ophthalmic
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35569
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_77716
manufacturer_name
Cardinal Health 110,Inc
package_marketing_start_date
20160830
rxcui
2391754
unii
K89MJ0S5VY
spl_set_id
b15eb271-7842-495b-aa0f-9b20def86dc1
has_treatment
http://purl.obolibrary.org/obo/DOID_0060260
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_77716
owl#someValuesFrom
t3103794
owl#annotatedSource
t300673
active_ingredient_strength
30 g/1
active_ingredient_name
OXYMETAZOLINE HYDROCHLORIDE
core#notation
CHEBI:7862
pharm_class
Vasoconstrictor [EPC]
brand_name_suffix
Clear and Cool
upc
0050428610862
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class