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Pemoline

CHEBI:CHEBI_7953

Definition

A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

Chemical Information

Molecular Formula
C9H8N2O2
Molecular Mass
176.17200
Charge
0
SMILES
NC1=NC(=O)C(O1)c1ccccc1
InChI
InChI=1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12)
InChIKey
NRNCYVBFPDDJNE-UHFFFAOYSA-N

Alternative Names

  • 2-amino-5-phenyl-1,3-oxazol-4(5H)-one
  • 2-Amino-5-phenyl-4(5H)-oxazolone
  • 2-imino-4-keto-5-phenyltetrahydrooxazole
  • 2-imino-5-phenyl-4-oxazolidinone
  • 5-phenyl-2-imino-4-oxazolidinone
  • 5-phenyl-2-imino-4-oxooxazolidine
  • 5-phenylisohydantion
  • Azoxodon
  • Betanamin
  • Cylert
  • Dantromin
  • Deltamine
  • Hyton
  • Myamin
  • Nitan
  • Notair
  • pemolina
  • pemoline
  • pemolinum
  • pheniminooxazolidinone
  • phenylisohydantoin
  • phenylpseudohydantoin

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
7966
oboInOwl#hasDbXref
Wikipedia:Pemoline
core#notation
CHEBI:7953

Additional References

Wikipedia:Pemoline

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Additional Attributes

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chebi_ontology
DRON_00010000
7966
oboInOwl#hasDbXref
Wikipedia:Pemoline
oboInOwl#id
CHEBI:7953
core#notation
CHEBI:7953
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35337
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_100703
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t300704
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t956931