Discuss This Drug

penciclovir

CHEBI:CHEBI_7956

Definition

A member of the class of 2-aminopurines that is guanine in which the hydrogen at position 9 is substituted by a 4-hydroxy-3-(hydroxymethyl)but-1-yl group. An antiviral drug, it is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration.

Chemical Information

Molecular Formula
C10H15N5O3
Molecular Mass
253.25780
Charge
0
SMILES
Nc1nc2n(CCC(CO)CO)cnc2c(=O)[nH]1
InChI
InChI=1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18)
InChIKey
JNTOCHDNEULJHD-UHFFFAOYSA-N

Alternative Names

  • 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1,9-dihydro-6H-purin-6-one
  • 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine
  • 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine
  • 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine
  • 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine
  • PCV
  • PE2
  • penciclovir
  • penciclovirum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
59839
oboInOwl#hasDbXref
Wikipedia:Penciclovir
core#notation
CHEBI:7956

Additional References

Wikipedia:Penciclovir

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
59839
oboInOwl#hasDbXref
Wikipedia:Penciclovir
oboInOwl#hasAlternativeId
CHEBI:44870
oboInOwl#id
CHEBI:7956
generic_name
PENCICLOVIR
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
CREAM
route
TOPICAL
marketing_start_date
20200925
labeler_name
Zhejiang Charioteer Pharmaceutical Co., Ltd.
brand_name
Denavir
brand_name_base
Denavir
product_ndc
0378-9720
spl_id
ed286bc3-dda6-4f75-9338-3eb0987a2a7d
package_ndc
0378-9720-55
application_number
ANDA212368
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36044
oboInOwl#inSubset
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chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_16235
core#notation
CHEBI:7956
rxcui
211343
nui
N0000175459
pharm_class_epc
Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
pharm_class
Nucleoside Analog [EXT]
pharm_class_moa
DNA Polymerase Inhibitors [MoA]
package_marketing_start_date
31-JUL-16
active_ingredient_strength
7 kg/7kg
manufacturer_name
Mylan Pharmaceuticals Inc.
active_ingredient_name
PENCICLOVIR
package_description
1 TUBE in 1 CARTON (0378-9720-55) / 5 g in 1 TUBE
unii
359HUE8FJC
spl_set_id
61229829-55a0-4d6f-a423-4b48a2b4d8e5
upc
0300933186209
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
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https://w3id.org/def/predibionto#has_drug_113306
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http://purl.obolibrary.org/obo/DOID_8566
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https://w3id.org/def/predibionto#has_side_effect35645
owl#annotatedSource
t300684
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