penciclovir

CHEBI:CHEBI_7956

Definition

A member of the class of 2-aminopurines that is guanine in which the hydrogen at position 9 is substituted by a 4-hydroxy-3-(hydroxymethyl)but-1-yl group. An antiviral drug, it is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration.

Chemical Information

Molecular Formula
C10H15N5O3
Molecular Mass
253.25780
Charge
0
SMILES
Nc1nc2n(CCC(CO)CO)cnc2c(=O)[nH]1
InChI
InChI=1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18)
InChIKey
JNTOCHDNEULJHD-UHFFFAOYSA-N

Alternative Names

  • 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1,9-dihydro-6H-purin-6-one
  • 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine
  • 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine
  • 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine
  • 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine
  • PCV
  • PE2
  • penciclovir
  • penciclovirum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
59839
oboInOwl#hasDbXref
Wikipedia:Penciclovir
core#notation
CHEBI:7956

Additional References

Wikipedia:Penciclovir

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
59839
oboInOwl#hasDbXref
Wikipedia:Penciclovir
oboInOwl#hasAlternativeId
CHEBI:44870
oboInOwl#id
CHEBI:7956
core#notation
CHEBI:7956
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36044
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_16235
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113306
has_treatment
http://purl.obolibrary.org/obo/DOID_8566
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect35645
owl#annotatedSource
t300684
owl#someValuesFrom
t550182