Discuss This Drug

Phentolamine

CHEBI:CHEBI_8081

Definition

A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Chemical Information

Molecular Formula
C17H19N3O
Molecular Mass
281.35230
Charge
0
SMILES
Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1
InChI
InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)
InChIKey
MRBDMNSDAVCSSF-UHFFFAOYSA-N

Alternative Names

  • 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline
  • 3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol
  • fentolamina
  • phentolamine
  • Phentolamine mesylate
  • phentolaminum
  • Regitina
  • Regitine
  • Rogitine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Phentolamine
DRON_00010000
8153
core#notation
CHEBI:8081

Additional References

Wikipedia:Phentolamine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Phentolamine
DRON_00010000
8153
oboInOwl#id
CHEBI:8081
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
INJECTION, POWDER, FOR SOLUTION
marketing_start_date
20170715
generic_name
Phentolamine Mesylate
brand_name
Oraverse
brand_name_base
Oraverse
product_ndc
42973-389
application_number
ANDA207686
labeler_name
RAKSHIT DRUGS PRIVATE LIMITED
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37890
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:8081
rxcui
2677798
active_ingredient_strength
.235 mg/mL
pharm_class
alpha-Adrenergic Blocker [EPC]
package_marketing_start_date
12-APR-24
manufacturer_name
Septodont, Inc.
active_ingredient_name
PHENTOLAMINE MESYLATE
unii
Y7543E5K9T
spl_set_id
fe1e10f5-4ff3-4616-9534-489648d88d33
package_description
1 g in 1 CONTAINER (71052-285-00)
upc
0351224012202
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
listing_expiration_date
20241231
route
SUBMUCOSAL
spl_id
199680dc-7dc0-765c-e063-6394a90a9914
package_ndc
42973-389-00
owl#annotatedSource
t304174
owl#someValuesFrom
t3069185