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Phentolamine

CHEBI:CHEBI_8081

Definition

A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Chemical Information

Molecular Formula
C17H19N3O
Molecular Mass
281.35230
Charge
0
SMILES
Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1
InChI
InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)
InChIKey
MRBDMNSDAVCSSF-UHFFFAOYSA-N

Alternative Names

  • 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline
  • 3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol
  • fentolamina
  • phentolamine
  • Phentolamine mesylate
  • phentolaminum
  • Regitina
  • Regitine
  • Rogitine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Phentolamine
DRON_00010000
8153
core#notation
CHEBI:8081

Additional References

Wikipedia:Phentolamine

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Additional Attributes

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chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Phentolamine
DRON_00010000
8153
oboInOwl#id
CHEBI:8081
core#notation
CHEBI:8081
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37890
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#annotatedSource
t304174
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t3069185