pioglitazone
CHEBI:CHEBI_8228
Definition
A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Chemical Information
- Molecular Formula
- C19H20N2O3S
- Molecular Mass
- 356.43978
- Charge
- 0
- SMILES
- CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1
- InChI
- InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)
- InChIKey
- HYAFETHFCAUJAY-UHFFFAOYSA-N
Alternative Names
- (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
- 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
- pioglitazona
- pioglitazone
- Pioglitazone
- pioglitazonum
Drug Classification
-
pyridinesView Class →
CHEBI:26421
-
aromatic etherView Class →
CHEBI:35618
-
thiazolidinedionesView Class →
CHEBI:50990
-
t303467
-
t303558
-
t303590
-
t303770
-
t303816
-
t303906
-
t303941
-
t304001
-
t304071
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Pioglitazone
- DRON_00010000
- 33738
- core#notation
- CHEBI:8228
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Pioglitazone
- DRON_00010000
- 33738
- oboInOwl#id
- CHEBI:8228
- core#notation
- CHEBI:8228
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_83157
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_11712
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect36064
- owl#annotatedSource
- t304093
- owl#someValuesFrom
- t3005090