pioglitazone

CHEBI:CHEBI_8228

Definition

A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.

Chemical Information

Molecular Formula
C19H20N2O3S
Molecular Mass
356.43978
Charge
0
SMILES
CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1
InChI
InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)
InChIKey
HYAFETHFCAUJAY-UHFFFAOYSA-N

Alternative Names

  • (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
  • 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
  • pioglitazona
  • pioglitazone
  • Pioglitazone
  • pioglitazonum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Pioglitazone
DRON_00010000
33738
core#notation
CHEBI:8228

Additional References

Wikipedia:Pioglitazone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
labeler_name
Teva API India Limited
marketing_category
ANDA
marketing_start_date
20030303
application_number
NDA021925
spl_id
1dd2c002-73ff-b183-e063-6294a90a5b65
package_ndc
63629-3299-1
product_type
BULK INGREDIENT
dosage_form
POWDER
product_ndc
71335-9664
rxcui
731463
manufacturer_name
REMEDYREPACK INC.
unii
X4OV71U42S
spl_set_id
f434ba0d-13f3-42ae-a2d5-cddb93fde1e8
package_marketing_start_date
20170123
route
ORAL
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Pioglitazone
DRON_00010000
33738
oboInOwl#id
CHEBI:8228
generic_name
Pioglitazone hydrochloride
brand_name
Duetact
brand_name_base
Duetact
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_83157
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
package_description
30 TABLET in 1 BOTTLE (42291-959-30)
core#notation
CHEBI:8228
pharm_class
Peroxisome Proliferator-activated Receptor gamma Agonists [MoA]
pharm_class_epc
Thiazolidinedione [EPC]
pharm_class_moa
Peroxisome Proliferator-activated Receptor gamma Agonists [MoA]
pharm_class_cs
Thiazolidinediones [CS]
upc
0368071217032
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
active_ingredient_strength
850 mg/1
active_ingredient_name
PIOGLITAZONE
nui
M0447306
has_treatment
http://purl.obolibrary.org/obo/DOID_11712
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect36064
owl#annotatedSource
t304093
owl#someValuesFrom
t3005090