Discuss This Drug

Suvorexant

CHEBI:CHEBI_82698

Definition

An aromatic amide obtained by formal condensation of the carboxy group of 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid with the secondary amino group of 5-chloro-2-[(5R)-5-methyl-1,4-diazepan-1-yl]-1,3-benzoxazole. An orexin receptor antagonist used for the management of insomnia.

Chemical Information

Molecular Formula
C23H23ClN6O2
Molecular Mass
450.92100
Charge
0
SMILES
C[C@@H]1CCN(CCN1C(=O)c1cc(C)ccc1-n1nccn1)c1nc2cc(Cl)ccc2o1
InChI
InChI=1S/C23H23ClN6O2/c1-15-3-5-20(30-25-8-9-26-30)18(13-15)22(31)29-12-11-28(10-7-16(29)2)23-27-19-14-17(24)4-6-21(19)32-23/h3-6,8-9,13-14,16H,7,10-12H2,1-2H3/t16-/m1/s1
InChIKey
JYTNQNCOQXFQPK-MRXNPFEDSA-N

Alternative Names

  • [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone
  • BELSOMRA
  • MK 4305
  • MK-4305
  • MK4305
  • suvorexant

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1547099
oboInOwl#hasDbXref
Wikipedia:Suvorexant
core#notation
CHEBI:82698

Additional References

Wikipedia:Suvorexant

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1547099
brand_name
BELSOMRA
brand_name_base
BELSOMRA
oboInOwl#hasDbXref
Wikipedia:Suvorexant
oboInOwl#id
CHEBI:82698
generic_name
Suvorexant
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20251231
route
ORAL
dosage_form
POWDER
marketing_start_date
20140815
labeler_name
Merck Sharp & Dohme LLC.
product_ndc
0006-0004
application_number
NDA204569
spl_id
d3873dcd-6935-4c82-8b06-b38f0661a472
package_ndc
0006-0004-01
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_83296
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:82698
rxcui
1547575
active_ingredient_strength
1 kg/kg
dea_schedule
CIV
pharm_class_moa
Orexin Receptor Antagonists [MoA]
pharm_class
Orexin Receptor Antagonists [MoA]
nui
N0000190998
manufacturer_name
Merck Sharp & Dohme LLC
package_marketing_start_date
13-AUG-14
pharm_class_epc
Orexin Receptor Antagonist [EPC]
active_ingredient_name
SUVOREXANT
package_description
1 BAG in 1 DRUM (0006-0004-01) / 120000 TABLET, FILM COATED in 1 BAG
unii
081L192FO9
spl_set_id
e5b72731-1acb-45b7-9c13-290ad12d3951
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_535
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect36181
owl#annotatedSource
t304166
owl#someValuesFrom
t2910019