Discuss This Drug

tedizolid

CHEBI:CHEBI_82717

Definition

A member of the class of pyridines that is pyridine which is substituted by a 2-methyl-2H-tetrazol-5-yl group at position 2 and by a 2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl group at position 5. It is used as its phosphate pro-drug used for the treatment of acute bacterial skin and skin structure infections caused by certain susceptible bacteria, including Staphylococcus aureus (including methicillin-resistant strains (MRSA) and methicillin-susceptible strains), various Streptococcus species, and Enterococcus faecalis.

Chemical Information

Molecular Formula
C17H15FN6O3
Molecular Mass
370.338
Charge
0
SMILES
C1=C(C=CC(=C1F)C2=CN=C(C=C2)C=3N=NN(N3)C)N4C(O[C@H](C4)CO)=O
InChI
InChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1
InChIKey
XFALPSLJIHVRKE-GFCCVEGCSA-N

Alternative Names

  • (5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one
  • DA 7157
  • DA-7157
  • tedizolid
  • Torezolid
  • TR 700
  • TR-700

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:82717
DRON_00010000
1540825
oboInOwl#hasDbXref
Wikipedia:Tedizolid

Additional References

Wikipedia:Tedizolid

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:82717
pharm_class
Oxazolidinones [CS]
active_ingredient_strength
200 mg/4mL
active_ingredient_name
TEDIZOLID PHOSPHATE
spl_set_id
75672079-589f-451a-bdbf-eaebcfcc80a9
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1540825
oboInOwl#hasDbXref
Wikipedia:Tedizolid
oboInOwl#id
CHEBI:82717
rxcui
1540890
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20251231
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
route
INTRAVENOUS
labeler_name
Nabriva Therapeutics US, Inc.
manufacturer_name
Nabriva Therapeutics US, Inc.
generic_name
Tedizolid Phosphate
product_ndc
65392-2912
marketing_start_date
20140620
spl_id
eb8db7d5-6fe6-4ba6-e053-2995a90ae3da
package_ndc
65392-2912-0
package_description
15 kg in 1 DRUM (65392-2912-0)
package_marketing_start_date
20-JUN-14
brand_name
SIVEXTRO
brand_name_base
SIVEXTRO
application_number
NDA205436
unii
O7DRJ6R4DW
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_48001
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_110730
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect36285
owl#annotatedSource
t304172
owl#someValuesFrom
t3009102