Discuss This Drug

efinaconazole

CHEBI:CHEBI_82718

Definition

A member of the class of triazoles that is butan-2-ol which is substituted at positions 1, 2, and 3 by 1,2,4-triazol-1-yl, 2,4-difluorophenyl, and 4-methylenepiperidin-1-yl groups, respectively (the 2R,3R stereoisomer). It is an antifungal drug used for the topical treatment of onychomycosis (a nail infection caused mainly by dermatophytes).

Chemical Information

Molecular Formula
C18H22F2N4O
Molecular Mass
348.39030
Charge
0
SMILES
C[C@@H](N1CCC(=C)CC1)[C@](O)(Cn1cncn1)c1ccc(F)cc1F
InChI
InChI=1S/C18H22F2N4O/c1-13-5-7-23(8-6-13)14(2)18(25,10-24-12-21-11-22-24)16-4-3-15(19)9-17(16)20/h3-4,9,11-12,14,25H,1,5-8,10H2,2H3/t14-,18-/m1/s1
InChIKey
NFEZZTICAUWDHU-RDTXWAMCSA-N

Alternative Names

  • (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
  • efinaconazol
  • efinaconazole
  • efinaconazolum
  • JUBLIA
  • KP-103

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:82718
oboInOwl#hasDbXref
Wikipedia:Efinaconazole
DRON_00010000
1539753

Additional References

Wikipedia:Efinaconazole

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect36287
owl#annotatedSource
t304143
owl#someValuesFrom
t2987464
core#notation
CHEBI:82718
rxcui
1539762
listing_expiration_date
20241231
route
TOPICAL
pharm_class_epc
Azole Antifungal [EPC]
pharm_class
Azoles [CS]
pharm_class_cs
Azoles [CS]
active_ingredient_strength
10 kg/10kg
nui
M0002083
package_marketing_start_date
20-JUL-14
manufacturer_name
Bausch Health US LLC
spl_id
1f82ea60-7c18-81ff-e063-6294a90ae2b8
active_ingredient_name
EFINACONAZOLE
package_ndc
58175-0606-0
package_description
1 BAG in 1 DRUM (58175-0606-0) / 50 kg in 1 BAG
unii
J82SB7FXWB
spl_set_id
922d4d25-c530-11e1-9b21-0800200c9a66
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Efinaconazole
DRON_00010000
1539753
oboInOwl#id
CHEBI:82718
generic_name
EFINACONAZOLE
brand_name
JUBLIA
brand_name_base
JUBLIA
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
POWDER, FOR SOLUTION
marketing_start_date
20140720
labeler_name
KAKEN Pharmaceutical Co., LTD
product_ndc
58175-0606
application_number
NDA203567
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77884