Discuss This Drug

empagliflozin

CHEBI:CHEBI_82720

Definition

A C-glycosyl compound consisting of a beta-glucosyl residue having a (4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl group at the anomeric centre. A sodium-glucose co-transporter 2 inhibitor used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Chemical Information

Molecular Formula
C23H27ClO7
Molecular Mass
450.90900
Charge
0
SMILES
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(O[C@H]3CCOC3)cc2)c1
InChI
InChI=1S/C23H27ClO7/c24-18-6-3-14(23-22(28)21(27)20(26)19(11-25)31-23)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21-,22+,23-/m0/s1
InChIKey
OBWASQILIWPZMG-QZMOQZSNSA-N

Alternative Names

  • (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol
  • (1S)-1,5-anhydro-1-C-{4-chloro-3-((4-{((3S)-oxolan-3-yl)oxy}phenyl)methyl)phenyl}-D-glucitol
  • 1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy)benzyl)benzene
  • BI 10773
  • BI-10773
  • BI10773
  • empagliflozin
  • JARDIANCE

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:82720
DRON_00010000
1545653
oboInOwl#hasDbXref
Wikipedia:Empagliflozin

Additional References

Wikipedia:Empagliflozin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:82720
pharm_class
Dipeptidyl Peptidase 4 Inhibitors [MoA]
pharm_class_moa
Dipeptidyl Peptidase 4 Inhibitors [MoA]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
POWDER
marketing_start_date
20180602
labeler_name
BOEHRINGER INGELHEIM HELLAS SINGLE MEMBER S.A.
spl_id
691d5f55-2b16-4cf3-9cef-efa755e11127
package_ndc
0597-0152-90
application_number
NDA206073
product_ndc
67835-0024
rxcui
1602120
active_ingredient_strength
10 mg/10mg
active_ingredient_name
LINAGLIPTIN
unii
3X29ZEJ4R2
package_marketing_start_date
02-JUN-18
manufacturer_name
Cardinal Health 107, LLC
nui
N0000175913
pharm_class_epc
Dipeptidyl Peptidase 4 Inhibitor [EPC]
spl_set_id
faf3dd6a-9cd0-39c2-0d2e-232cb3f67565
upc
0355154041288
package_description
60 mg in 1 DRUM (83145-015-99)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1545653
oboInOwl#hasDbXref
Wikipedia:Empagliflozin
oboInOwl#id
CHEBI:82720
generic_name
Empagliflozin (Process II)
brand_name
Glyxambi
brand_name_base
Glyxambi
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_73273
has_treatment
http://purl.obolibrary.org/obo/DOID_0050728
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect36345
owl#annotatedSource
t304126
owl#someValuesFrom
t3511218