empagliflozin
CHEBI:CHEBI_82720
Definition
A C-glycosyl compound consisting of a beta-glucosyl residue having a (4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl group at the anomeric centre. A sodium-glucose co-transporter 2 inhibitor used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Chemical Information
- Molecular Formula
- C23H27ClO7
- Molecular Mass
- 450.90900
- Charge
- 0
- SMILES
- OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(O[C@H]3CCOC3)cc2)c1
- InChI
- InChI=1S/C23H27ClO7/c24-18-6-3-14(23-22(28)21(27)20(26)19(11-25)31-23)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21-,22+,23-/m0/s1
- InChIKey
- OBWASQILIWPZMG-QZMOQZSNSA-N
Alternative Names
- (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol
- (1S)-1,5-anhydro-1-C-{4-chloro-3-((4-{((3S)-oxolan-3-yl)oxy}phenyl)methyl)phenyl}-D-glucitol
- 1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy)benzyl)benzene
- BI 10773
- BI-10773
- BI10773
- empagliflozin
- JARDIANCE
Drug Classification
-
aromatic etherView Class →
CHEBI:35618
-
monochlorobenzenesView Class →
CHEBI:83403
-
C-glycosyl compoundView Class →
CHEBI:20857
-
tetrahydrofuryl etherView Class →
CHEBI:47814
-
t303348
-
t303523
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1545653
- oboInOwl#hasDbXref
- Wikipedia:Empagliflozin
- core#notation
- CHEBI:82720
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1545653
- oboInOwl#hasDbXref
- Wikipedia:Empagliflozin
- oboInOwl#id
- CHEBI:82720
- core#notation
- CHEBI:82720
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_73273
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0050728
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect36345
- owl#annotatedSource
- t304126
- owl#someValuesFrom
- t3511218