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eliglustat

CHEBI:CHEBI_82752

Definition

A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltransferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease.

Chemical Information

Molecular Formula
C23H36N2O4
Molecular Mass
404.54290
Charge
0
SMILES
CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)c1ccc2OCCOc2c1
InChI
InChI=1S/C23H36N2O4/c1-2-3-4-5-6-9-22(26)24-19(17-25-12-7-8-13-25)23(27)18-10-11-20-21(16-18)29-15-14-28-20/h10-11,16,19,23,27H,2-9,12-15,17H2,1H3,(H,24,26)/t19-,23-/m1/s1
InChIKey
FJZZPCZKBUKGGU-AUSIDOKSSA-N

Alternative Names

  • eliglustat
  • Genz 99067
  • Genz-99067
  • N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1547220
oboInOwl#hasDbXref
Wikipedia:Eliglustat
core#notation
CHEBI:82752

Additional References

Wikipedia:Eliglustat

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rdf-schema#range
https://w3id.org/def/predibionto#has_drug_105296
has_treatment
http://purl.obolibrary.org/obo/DOID_0110957
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect36381
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_83355
owl#annotatedSource
t304180
owl#someValuesFrom
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oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1547220
oboInOwl#hasDbXref
Wikipedia:Eliglustat
oboInOwl#id
CHEBI:82752
core#notation
CHEBI:82752
listing_expiration_date
20241231
dosage_form
POWDER
marketing_start_date
20140819
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
active_ingredient_strength
1 kg/kg
package_marketing_start_date
19-AUG-14
labeler_name
Maithri Laboratories Private Limited
generic_name
Eliglustat Tartrate (Amorphous)
active_ingredient_name
ELIGLUSTAT TARTRATE
product_ndc
65977-0151
spl_id
148d68cf-2459-0155-e063-6394a90affb8
package_ndc
65977-0151-1
package_description
1 kg in 1 DRUM (65977-0151-1)
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50382
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_83355
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class