Discuss This Drug

fosamprenavir

CHEBI:CHEBI_82941

Definition

A sulfonamide with a structure based on that of sulfanilamide substituted on the sulfonamide nitrogen by a (2R,3S)-4-phenyl-2-(phosphonooxy)-3-({[(3S)-tetrahydrofuran-3-yloxy]carbonyl}amino)butyl group. It is a pro-drug of the HIV protease inhibitor and antiretroviral drug amprenavir.

Chemical Information

Molecular Formula
C25H36N3O9PS
Molecular Mass
585.60700
Charge
0
SMILES
CC(C)CN(C[C@@H](OP(O)(O)=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CCOC1)S(=O)(=O)c1ccc(N)cc1
InChI
InChI=1S/C25H36N3O9PS/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32)/t21-,23-,24+/m0/s1
InChIKey
MLBVMOWEQCZNCC-OEMFJLHTSA-N

Alternative Names

  • (3S)-tetrahydrofuran-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-1-phenyl-3-(phosphonooxy)butan-2-yl]carbamate
  • FOS-APV
  • fosamprenavir

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:82941
oboInOwl#hasDbXref
Wikipedia:Fosamprenavir
DRON_00010000
358262

Additional References

Wikipedia:Fosamprenavir

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
core#notation
CHEBI:82941
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Fosamprenavir
DRON_00010000
358262
oboInOwl#id
CHEBI:82941
rxcui
402109
product_type
BULK INGREDIENT
listing_expiration_date
20251231
route
ORAL
marketing_category
BULK INGREDIENT
dosage_form
TABLET, COATED
pharm_class
P-Glycoprotein Inducers [MoA]
marketing_start_date
20191128
package_marketing_start_date
20191128
active_ingredient_strength
1 kg/kg
labeler_name
Mylan Pharmaceuticals Inc.
manufacturer_name
Mylan Pharmaceuticals Inc.
generic_name
Fosamprenavir Calcium
active_ingredient_name
FOSAMPRENAVIR CALCIUM
brand_name
Fosamprenavir Calcium
brand_name_base
Fosamprenavir Calcium
product_ndc
63304-583
application_number
ANDA204024
spl_id
5206523f-bf38-40fb-8565-e18abdfe8ed0
package_ndc
63304-583-60
package_description
60 TABLET, COATED in 1 BOTTLE (63304-583-60)
unii
ID1GU2627N
spl_set_id
5cd1eead-9fc1-426c-bee8-214ffa7d9dc1
upc
0303783520919
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_45373
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect36449
owl#annotatedSource
t304088
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