Discuss This Drug

Raltegravir

CHEBI:CHEBI_82960

Definition

A pyrimidone that is pyrimidin-4(3H)-one in which the hydrogens at positions 2, 3, 5 and 6 are replaced by 2-[(5-methyl-1,3,4-oxadiazole-2-carbonyl)amino]propan-2-yl, methyl, hydroxy, and N-[(4-fluorophenyl)methyl]aminoacyl groups, respectively. It is an antiretroviral drug used for treatment of HIV infection.

Chemical Information

Molecular Formula
C20H21FN6O5
Molecular Mass
444.423
Charge
0
SMILES
CN1C(=O)C(O)=C(N=C1C(C)(C)NC(=O)C1=NN=C(C)O1)C(=O)NCC1=CC=C(F)C=C1
InChI
InChI=1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30)
InChIKey
CZFFBEXEKNGXKS-UHFFFAOYSA-N

Alternative Names

  • MK 0518
  • MK-0518
  • MK0518
  • N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(2-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}propan-2-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide
  • raltegravir
  • raltegravirum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:82960
oboInOwl#hasDbXref
Wikipedia:Raltegravir
DRON_00010000
719872

Additional References

Wikipedia:Raltegravir

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
ORAL
labeler_name
NuCare Pharmaceuticals,Inc.
marketing_start_date
20011012
spl_id
4cb3ef64-0fec-45c7-9c7f-5cca90c7a517
package_ndc
71205-777-90
package_description
90 TABLET, FILM COATED in 1 BOTTLE (71205-777-90)
application_number
NDA205786
core#notation
CHEBI:82960
rxcui
1924315
manufacturer_name
NuCare Pharmaceuticals,Inc.
active_ingredient_strength
1 kg/kg
package_marketing_start_date
28-MAY-08
active_ingredient_name
RALTEGRAVIR POTASSIUM
unii
43Y000U234
spl_set_id
ccc6f2f9-696f-4ef9-bb4c-e0198d957b0b
pharm_class
Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor [EPC]
upc
0371205777142
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Raltegravir
DRON_00010000
719872
oboInOwl#id
CHEBI:82960
generic_name
raltegravir potassium
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
GRANULE, FOR SUSPENSION
product_ndc
71205-777
brand_name
ISENTRESS
brand_name_base
ISENTRESS
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_67268
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
owl#annotatedSource
t304104
owl#someValuesFrom
t3068627