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olaparib

CHEBI:CHEBI_83766

Definition

A member of the class of N-acylpiperazines obtained by formal condensation of the carboxy group of 2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoic acid with the free amino group of N-(cyclpropylcarbonyl)piperazine; used to treat advanced ovarian cancer.

Chemical Information

Molecular Formula
C24H23FN4O3
Molecular Mass
434.46280
Charge
0
SMILES
Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)C1CC1
InChI
InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30)
InChIKey
FDLYAMZZIXQODN-UHFFFAOYSA-N

Alternative Names

  • 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one
  • AZD-2281
  • AZD2281
  • KU59436
  • Lynparza
  • olaparib

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1597582
oboInOwl#hasDbXref
Wikipedia:Olaparib
core#notation
CHEBI:83766

Additional References

Wikipedia:Olaparib

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Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1597582
oboInOwl#hasDbXref
Wikipedia:Olaparib
oboInOwl#id
CHEBI:83766
core#notation
CHEBI:83766
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68495
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http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_5746
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect36598
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t307600
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t3174515