Discuss This Drug

olaparib

CHEBI:CHEBI_83766

Definition

A member of the class of N-acylpiperazines obtained by formal condensation of the carboxy group of 2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoic acid with the free amino group of N-(cyclpropylcarbonyl)piperazine; used to treat advanced ovarian cancer.

Chemical Information

Molecular Formula
C24H23FN4O3
Molecular Mass
434.46280
Charge
0
SMILES
Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)C1CC1
InChI
InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30)
InChIKey
FDLYAMZZIXQODN-UHFFFAOYSA-N

Alternative Names

  • 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one
  • AZD-2281
  • AZD2281
  • KU59436
  • Lynparza
  • olaparib

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1597582
oboInOwl#hasDbXref
Wikipedia:Olaparib
core#notation
CHEBI:83766

Additional References

Wikipedia:Olaparib

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1597582
oboInOwl#hasDbXref
Wikipedia:Olaparib
oboInOwl#id
CHEBI:83766
generic_name
Olaparib Form A
listing_expiration_date
20241231
dosage_form
POWDER
marketing_start_date
20141219
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
product_ndc
46708-904
labeler_name
Alembic Pharmaceuticals Limited
spl_id
c75aacf5-3835-46ac-ba37-7c08e32ed4dc
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68495
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:83766
active_ingredient_strength
25 kg/25kg
active_ingredient_name
OLAPARIB
package_ndc
46708-904-25
package_description
25 kg in 1 DRUM (46708-904-25)
package_marketing_start_date
05-AUG-20
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_5746
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect36598
owl#annotatedSource
t307600
owl#someValuesFrom
t3174515