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Triprolidine

CHEBI:CHEBI_84116

Definition

An N-alkylpyrrolidine that is acrivastine in which the pyridine ring is lacking the propenoic acid substituent. It is a sedating antihistamine that is used (generally as the monohydrochloride monohydrate) for the relief of the symptoms of uticaria, rhinitis, and various pruritic skin disorders.

Chemical Information

Molecular Formula
C19H22N2
Molecular Mass
278.39140
Charge
0
SMILES
Cc1ccc(cc1)C(=C/CN1CCCC1)\c1ccccn1
InChI
InChI=1S/C19H22N2/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21/h2-3,6-12H,4-5,13-15H2,1H3/b18-11+
InChIKey
CBEQULMOCCWAQT-WOJGMQOQSA-N

Alternative Names

  • (E)-2-[3-(1-pyrrolidinyl)-1-p-toluenepropenyl]pyridine
  • 2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine
  • trans-1-(2-pyridyl)-3-pyrrolidino-1-p-tolylprop-1-ene
  • trans-1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene
  • trans-2-(3-(1-pyrrolidinyl)-1-p-tolylpropenyl)pyridine
  • tripolidina
  • triprolidine
  • triprolidinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
10849
oboInOwl#hasDbXref
Wikipedia:Triprolidine
core#notation
CHEBI:84116

Additional References

Wikipedia:Triprolidine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
10849
oboInOwl#hasDbXref
Wikipedia:Triprolidine
oboInOwl#id
CHEBI:84116
listing_expiration_date
20241231
dosage_form
SYRUP
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
marketing_start_date
20030823
application_number
M012
labeler_name
Brandywine Pharmaceuticals, LLC
generic_name
Triprolidine Hydrochloride
brand_name
FLONASE Nighttime Allergy Relief
brand_name_base
HISTEX PD Drops New Formulation
product_ndc
62331-046
spl_id
f21e5c00-3f3d-4cfa-aa59-da884278db4a
oboInOwl#inSubset
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RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37955
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_84117
core#notation
CHEBI:84116
rxcui
2623978
route
ORAL
active_ingredient_strength
1.25 mg/2mL
package_marketing_start_date
23-AUG-03
active_ingredient_name
TRIPROLIDINE HYDROCHLORIDE
unii
YAN7R5L890
pharm_class
Uncompetitive NMDA Receptor Antagonists [MoA]
manufacturer_name
Brandywine Pharmaceuticals, LLC
package_ndc
62331-046-31
package_description
50 kg in 1 DRUM (62331-046-31)
spl_set_id
070fb5a4-1848-41e8-90bf-57e682de1762
upc
0350991136166
brand_name_suffix
Nighttime Allergy Relief
22-rdf-syntax-ns#type
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http://purl.obolibrary.org/obo/CHEBI_84117
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t307595
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t3902390