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pristinamycin IA

CHEBI:CHEBI_8417

Definition

A cyclodepsipeptide that is (together with pristinamycin IIA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus.

Chemical Information

Molecular Formula
C45H54N8O10
Molecular Mass
866.95790
Charge
0
SMILES
CC[C@H]1NC(=O)[C@@H](NC(=O)c2ncccc2O)[C@@H](C)OC(=O)[C@@H](NC(=O)[C@@H]2CC(=O)CCN2C(=O)[C@H](Cc2ccc(cc2)N(C)C)N(C)C(=O)[C@@H]2CCCN2C1=O)c1ccccc1
InChI
InChI=1S/C45H54N8O10/c1-6-31-42(59)52-22-11-14-32(52)43(60)51(5)34(24-27-16-18-29(19-17-27)50(3)4)44(61)53-23-20-30(54)25-33(53)39(56)49-37(28-12-8-7-9-13-28)45(62)63-26(2)36(40(57)47-31)48-41(58)38-35(55)15-10-21-46-38/h7-10,12-13,15-19,21,26,31-34,36-37,55H,6,11,14,20,22-25H2,1-5H3,(H,47,57)(H,48,58)(H,49,56)/t26-,31-,32+,33+,34+,36+,37+/m1/s1
InChIKey
YGXCETJZBDTKRY-DZCVGBHJSA-N

Alternative Names

  • 4-[4-(Dimethylamino)-N-methyl-L-phenylalanine]virginiamycin S1
  • Antibiotic PA 114B
  • Antibiotic PA 114B1
  • Mikamycin B
  • NSC 92554
  • Ostreogrycin B
  • Pristinamycin IA
  • Streptogramin B
  • Vernamycin B alpha
  • N-[(6R,9S,10R,13S,15aS,22S,24aS)-22-{[4-(dimethylamino)phenyl]methyl}-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyldocosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl]-3-hydroxypyridine-2-carboxamide

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Pristinamycin_IA
core#notation
CHEBI:8417

Additional References

Wikipedia:Pristinamycin_IA

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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oboInOwl#hasDbXref
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CHEBI:8417
core#notation
CHEBI:8417
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http://purl.obolibrary.org/obo/CHEBI_76969
oboInOwl#inSubset
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http://www.w3.org/2002/07/owl#Class
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http://purl.obolibrary.org/obo/CHEBI_85274
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t309826