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palonosetron

CHEBI:CHEBI_85161

Definition

An organic heterotricyclic compound that is an antiemetic used (as its hydrochloride salt) in combination with netupitant (under the trade name Akynzeo) to treat nausea and vomiting in patients undergoing cancer chemotherapy.

Chemical Information

Molecular Formula
C19H24N2O
Molecular Mass
296.40670
Charge
0
SMILES
O=C1N(C[C@H]2CCCc3cccc1c23)[C@@H]1CN2CCC1CC2
InChI
InChI=1S/C19H24N2O/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20/h2,4,6,13,15,17H,1,3,5,7-12H2/t15-,17-/m1/s1
InChIKey
CPZBLNMUGSZIPR-NVXWUHKLSA-N

Alternative Names

  • (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one
  • 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one
  • palonosetron
  • palonosetronum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
70561
oboInOwl#hasDbXref
Wikipedia:Palonosetron
core#notation
CHEBI:85161

Additional References

Wikipedia:Palonosetron

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
70561
oboInOwl#hasDbXref
Wikipedia:Palonosetron
oboInOwl#id
CHEBI:85161
core#notation
CHEBI:85161
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50919
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_85163
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect37068
owl#annotatedSource
t310789
owl#someValuesFrom
t310836
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_85163