Discuss This Drug

palonosetron

CHEBI:CHEBI_85161

Definition

An organic heterotricyclic compound that is an antiemetic used (as its hydrochloride salt) in combination with netupitant (under the trade name Akynzeo) to treat nausea and vomiting in patients undergoing cancer chemotherapy.

Chemical Information

Molecular Formula
C19H24N2O
Molecular Mass
296.40670
Charge
0
SMILES
O=C1N(C[C@H]2CCCc3cccc1c23)[C@@H]1CN2CCC1CC2
InChI
InChI=1S/C19H24N2O/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20/h2,4,6,13,15,17H,1,3,5,7-12H2/t15-,17-/m1/s1
InChIKey
CPZBLNMUGSZIPR-NVXWUHKLSA-N

Alternative Names

  • (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one
  • 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one
  • palonosetron
  • palonosetronum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:85161
DRON_00010000
70561
oboInOwl#hasDbXref
Wikipedia:Palonosetron

Additional References

Wikipedia:Palonosetron

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
INTRAVENOUS
package_marketing_start_date
07-MAY-14
package_ndc
0409-2504-10
package_description
1 VIAL, SINGLE-DOSE in 1 CARTON (0409-2504-10) / 5 mL in 1 VIAL, SINGLE-DOSE
spl_id
0a3cbe8d-e85f-455c-ae44-5e91f3dbeb17
core#notation
CHEBI:85161
rxcui
2688839
active_ingredient_strength
.25 mg/2mL
manufacturer_name
Delpharm Boucherville Canada Inc.
pharm_class
Serotonin 3 Receptor Antagonists [MoA]
active_ingredient_name
PALONOSETRON HYDROCHLORIDE
unii
23310D4I19
spl_set_id
dff05900-7d15-424d-bf95-b7b60869fa97
upc
0363323673055
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
70561
oboInOwl#hasDbXref
Wikipedia:Palonosetron
oboInOwl#id
CHEBI:85161
generic_name
Palonosetron
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION
brand_name
PALONOSETRON
brand_name_base
PALONOSETRON
product_ndc
0409-2504
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50919
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_85163
listing_expiration_date
20241231
labeler_name
Delpharm Boucherville Canada Inc.
marketing_start_date
20030915
application_number
ANDA207005
owl#annotatedSource
t310789
owl#someValuesFrom
t310836
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect37068
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_85163