finafloxacin
CHEBI:CHEBI_85176
Definition
A quinolone that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted at positions 1, 6, 7 and 8 by cyclopropyl, fluoro, hexahydropyrrolo[3,4-b][1,4]oxazin-6-yl and cyano groups respectively; an antibiotic used for treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus.
Chemical Information
- Molecular Formula
- C20H19FN4O4
- Molecular Mass
- 398.38770
- Charge
- 0
- SMILES
- OC(=O)c1cn(C2CC2)c2c(C#N)c(N3C[C@@H]4NCCO[C@H]4C3)c(F)cc2c1=O
- InChI
- InChI=1S/C20H19FN4O4/c21-14-5-11-17(25(10-1-2-10)7-13(19(11)26)20(27)28)12(6-22)18(14)24-8-15-16(9-24)29-4-3-23-15/h5,7,10,15-16,23H,1-4,8-9H2,(H,27,28)/t15-,16-/m0/s1
- InChIKey
- FYMHQCNFKNMJAV-HOTGVXAUSA-N
Alternative Names
- 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
- finafloxacin
- Xtoro
Treatment Applications
-
malignant otitis externaView Disease →
DOID:10516
-
suppurative otitis mediaView Disease →
DOID:11506
-
patulous eustachian tubeView Disease →
DOID:12358
-
purulent labyrinthitisView Disease →
DOID:13534
-
chronic atticoantral diseaseView Disease →
DOID:14248
-
serous labyrinthitisView Disease →
DOID:1467
Drug Classification
-
nitrileView Class →
CHEBI:18379
-
quinoloneView Class →
CHEBI:23765
-
monocarboxylic acidView Class →
CHEBI:25384
-
cyclopropanesView Class →
CHEBI:51454
-
organofluorine compoundView Class →
CHEBI:37143
-
secondary amino compoundView Class →
CHEBI:50995
-
tertiary amino compoundView Class →
CHEBI:50996
-
t310062
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1598641
- oboInOwl#hasDbXref
- Wikipedia:Finafloxacin
- core#notation
- CHEBI:85176
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1598641
- oboInOwl#hasDbXref
- Wikipedia:Finafloxacin
- oboInOwl#id
- CHEBI:85176
- core#notation
- CHEBI:85176
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_36047
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_109011
- owl#annotatedSource
- t310915
- owl#someValuesFrom
- t3001081