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dasabuvir

CHEBI:CHEBI_85182

Definition

A member of the class of pyrimidone, which is (as the monohydrate of its sodium salt) in combination with ombitasvir, paritaprevir and ritonavir (under the trade name Viekira Pak) for treatment of chronic hepatitis C virus genotype 1 infection as well as cirrhosis of the liver.

Chemical Information

Molecular Formula
C26H27N3O5S
Molecular Mass
493.577
Charge
0
SMILES
C1=C(C=C2C(=C1)C=C(C=C2)C3=CC(=CC(=C3OC)C(C)(C)C)N4C=CC(NC4=O)=O)NS(C)(=O)=O
InChI
InChI=1S/C26H27N3O5S/c1-26(2,3)22-15-20(29-11-10-23(30)27-25(29)31)14-21(24(22)34-4)18-7-6-17-13-19(28-35(5,32)33)9-8-16(17)12-18/h6-15,28H,1-5H3,(H,27,30,31)
InChIKey
NBRBXGKOEOGLOI-UHFFFAOYSA-N

Alternative Names

  • ABT 333
  • dasabuvir
  • N-{6-[3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1597381
oboInOwl#hasDbXref
Wikipedia:Dasabuvir
core#notation
CHEBI:85182

Additional References

Wikipedia:Dasabuvir

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1597381
oboInOwl#hasDbXref
Wikipedia:Dasabuvir
oboInOwl#id
CHEBI:85182
core#notation
CHEBI:85182
listing_expiration_date
20251231
dosage_form
TABLET, FILM COATED
active_ingredient_strength
250 mg/1
product_type
DRUG FOR FURTHER PROCESSING
marketing_category
DRUG FOR FURTHER PROCESSING
labeler_name
AbbVie Ireland NL B.V.
marketing_start_date
20141107
generic_name
Dasabuvir
product_ndc
68513-3075
spl_id
90c93436-14f9-484e-b022-31fd05f72799
active_ingredient_name
DASABUVIR
package_ndc
68513-3075-9
package_description
20466 TABLET, FILM COATED in 1 DRUM (68513-3075-9)
package_marketing_start_date
07-NOV-14
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_85180
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_17568
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect37097
owl#annotatedSource
t310847
owl#someValuesFrom
t3037721