peramivir
CHEBI:CHEBI_85202
Definition
A member of the class of guanidines that is used (as its trihydrate) for the treatment of acute uncomplicated influenza in patients 18 years and older who have been symptomatic for no more than two days.
Chemical Information
- Molecular Formula
- C15H28N4O4
- Molecular Mass
- 328.40720
- Charge
- 0
- SMILES
- CCC(CC)[C@H](NC(C)=O)[C@@H]1[C@H](O)[C@H](C[C@H]1NC(N)=N)C(O)=O
- InChI
- InChI=1S/C15H28N4O4/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19)/t9-,10+,11+,12-,13+/m0/s1
- InChIKey
- XRQDFNLINLXZLB-CKIKVBCHSA-N
Alternative Names
- (1S,2S,3R,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-carbamimidamido-2-hydroxycyclopentane-1-carboxylic acid
- 3-(1'-acetylamino-2'-ethyl)butyl-4-((aminoimino)methyl)amino-2-hydroxycyclopentane-1-carboxylic acid
- BCX 1812
- BCX-1812
- BCX1812
- RWJ 270201
- RWJ-270201
- RWJ270201
Treatment Applications
-
asymptomatic dengueView Disease →
DOID:0050143
-
cryptogenic organizing pneumoniaView Disease →
DOID:0050157
-
obsolete influenza myocarditisView Disease →
DOID:0050163
-
obsolete influenza myositisView Disease →
DOID:0050164
-
Powassan encephalitisView Disease →
DOID:0050179
-
obsolete Rubella virus encephalitisView Disease →
DOID:0050187
-
obsolete influenza virus encephalitisView Disease →
DOID:0050191
-
Venezuelan hemorrhagic feverView Disease →
DOID:0050196
-
Whitewater Arroyo hemorrhagic feverView Disease →
DOID:0050199
-
swine influenzaView Disease →
DOID:0050211
-
dengue diseaseView Disease →
DOID:12205
-
West Nile encephalitisView Disease →
DOID:2365
-
encephalitisView Disease →
DOID:9588
-
mumpsView Disease →
DOID:10264
-
obsolete Mumps virus pancreatitisView Disease →
DOID:10312
-
chronic meningitisView Disease →
DOID:10341
-
obsolete coxsackie myocarditisView Disease →
DOID:10535
-
Eastern equine encephalitisView Disease →
DOID:10841
-
Murray Valley encephalitisView Disease →
DOID:10842
-
aseptic meningitisView Disease →
DOID:12157
-
obsolete equine encephalitisView Disease →
DOID:9585
Drug Classification
-
acetamidesView Class →
CHEBI:22160
-
guanidinesView Class →
CHEBI:24436
-
3-hydroxy monocarboxylic acidView Class →
CHEBI:35969
-
cyclopentanolsView Class →
CHEBI:23495
-
t310077
-
t310100
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 619693
- oboInOwl#hasDbXref
- Wikipedia:Peramivir
- core#notation
- CHEBI:85202
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 619693
- oboInOwl#hasDbXref
- Wikipedia:Peramivir
- oboInOwl#hasAlternativeId
- CHEBI:41095
- oboInOwl#id
- CHEBI:85202
- core#notation
- CHEBI:85202
- generic_name
- Peramivir
- rxcui
- 1598082
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- listing_expiration_date
- 20251231
- dosage_form
- SOLUTION
- pharm_class_epc
- Neuraminidase Inhibitor [EPC]
- pharm_class_moa
- Neuraminidase Inhibitors [MoA]
- route
- INTRAVENOUS
- active_ingredient_strength
- 1 kg/kg
- labeler_name
- BioCryst Pharmaceuticals, Inc.
- package_marketing_start_date
- 20141220
- marketing_start_date
- 20141220
- product_ndc
- 72769-181
- spl_id
- 21ecf2ba-0923-48bc-b8ca-53f7d8cff24d
- active_ingredient_name
- PERAMIVIR
- package_ndc
- 72769-181-03
- package_description
- 3 VIAL, GLASS in 1 CARTON (72769-181-03) / 20 mL in 1 VIAL, GLASS (72769-181-01)
- brand_name
- Rapivab
- brand_name_base
- Rapivab
- application_number
- NDA206426
- manufacturer_name
- BioCryst Pharmaceuticals, Inc.
- unii
- QW7Y7ZR15U
- spl_set_id
- fe04f6cd-e71c-4bd4-abac-97720bba2a0d
- nui
- N0000175436
- BFO_0000051
- http://purl.obolibrary.org/obo/CHEBI_85196
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_52425
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_4492
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113733
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect37127
- owl#annotatedSource
- t310984
- owl#someValuesFrom
- t3004508