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ivabradine

CHEBI:CHEBI_85966

Definition

A member of the class of benzazepines that is 7,8-dimethoxy-1,3,4,5-tetrahydro-3-benzazepin-2-one in which the amide hydrogen is replaced by a [{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl} group. Used (as its hydrochloride salt) to treat patients with angina who have intolerance to beta blockers and/or heart failure.

Chemical Information

Molecular Formula
C27H36N2O5
Molecular Mass
468.58510
Charge
0
SMILES
COc1cc2C[C@H](CN(C)CCCN3CCc4cc(OC)c(OC)cc4CC3=O)c2cc1OC
InChI
InChI=1S/C27H36N2O5/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30/h12-14,16,21H,6-11,15,17H2,1-5H3/t21-/m1/s1
InChIKey
ACRHBAYQBXXRTO-OAQYLSRUSA-N

Alternative Names

  • 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino]propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
  • ivabradine
  • S 16257
  • S 16257-2
  • S-16257
  • S-16257-2

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1649480
oboInOwl#hasDbXref
Wikipedia:Ivabradine
core#notation
CHEBI:85966

Additional References

Wikipedia:Ivabradine

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Additional Attributes

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chebi_ontology
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1649480
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http://purl.obolibrary.org/obo/CHEBI_38147
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http://www.w3.org/2002/07/owl#Class
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