edoxaban

CHEBI:CHEBI_85973

Definition

A monocarboxylic acid amide that is used (as its tosylate monohydrate) for the treatment of deep vein thrombosis and pulmonary embolism.

Chemical Information

Molecular Formula
C24H30ClN7O4S
Molecular Mass
548.05800
Charge
0
SMILES
CN(C)C(=O)[C@H]1CC[C@H](NC(=O)C(=O)Nc2ccc(Cl)cn2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1
InChI
InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15-,17+/m0/s1
InChIKey
HGVDHZBSSITLCT-JLJPHGGASA-N

Alternative Names

  • DU-176
  • edoxaban
  • N(1)-(5-chloropyridin-2-yl)-N(2)-{(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl}ethanediamide

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Edoxaban
DRON_00010000
1599538
core#notation
CHEBI:85973

Additional References

Wikipedia:Edoxaban

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Edoxaban
DRON_00010000
1599538
oboInOwl#id
CHEBI:85973
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
POWDER
marketing_start_date
20150112
labeler_name
Daiichi Sankyo Inc.
generic_name
Edoxaban Tosylate (Monohydrate)
product_ndc
42765-056
spl_id
f2fde029-6fa2-ba55-e053-2995a90a9355
package_ndc
42765-056-10
brand_name
SAVAYSA
brand_name_base
SAVAYSA
application_number
NDA206316
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68581
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_85976
core#notation
CHEBI:85973
rxcui
1599557
active_ingredient_strength
10 kg/10kg
package_marketing_start_date
21-FEB-22
active_ingredient_name
EDOXABAN TOSYLATE MONOHYDRATE
package_description
10 kg in 1 DRUM (42765-056-10)
pharm_class
Factor Xa Inhibitors [MoA]
manufacturer_name
Daiichi Sankyo Inc.
unii
32W99UE810
spl_set_id
e77d3400-56ad-11e3-949a-0800200c9a66
upc
0365597201309
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113241
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect37188
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_85976
owl#annotatedSource
t310978
owl#someValuesFrom
t3003836