edoxaban
CHEBI:CHEBI_85973
Definition
A monocarboxylic acid amide that is used (as its tosylate monohydrate) for the treatment of deep vein thrombosis and pulmonary embolism.
Chemical Information
- Molecular Formula
- C24H30ClN7O4S
- Molecular Mass
- 548.05800
- Charge
- 0
- SMILES
- CN(C)C(=O)[C@H]1CC[C@H](NC(=O)C(=O)Nc2ccc(Cl)cn2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1
- InChI
- InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15-,17+/m0/s1
- InChIKey
- HGVDHZBSSITLCT-JLJPHGGASA-N
Alternative Names
- DU-176
- edoxaban
- N(1)-(5-chloropyridin-2-yl)-N(2)-{(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl}ethanediamide
Treatment Applications
-
lateral sinus thrombosisView Disease →
DOID:3574
Drug Classification
-
monocarboxylic acid amideView Class →
CHEBI:29347
-
tertiary amino compoundView Class →
CHEBI:50996
-
chloropyridineView Class →
CHEBI:39173
-
thiazolopyridineView Class →
CHEBI:46956
-
t309992
-
t310039
-
t310438
-
t310804
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Edoxaban
- DRON_00010000
- 1599538
- core#notation
- CHEBI:85973
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Edoxaban
- DRON_00010000
- 1599538
- oboInOwl#id
- CHEBI:85973
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- route
- ORAL
- dosage_form
- POWDER
- marketing_start_date
- 20150112
- labeler_name
- Daiichi Sankyo Inc.
- generic_name
- Edoxaban Tosylate (Monohydrate)
- product_ndc
- 42765-056
- spl_id
- f2fde029-6fa2-ba55-e053-2995a90a9355
- package_ndc
- 42765-056-10
- brand_name
- SAVAYSA
- brand_name_base
- SAVAYSA
- application_number
- NDA206316
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_68581
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_85976
- core#notation
- CHEBI:85973
- rxcui
- 1599557
- active_ingredient_strength
- 10 kg/10kg
- package_marketing_start_date
- 21-FEB-22
- active_ingredient_name
- EDOXABAN TOSYLATE MONOHYDRATE
- package_description
- 10 kg in 1 DRUM (42765-056-10)
- pharm_class
- Factor Xa Inhibitors [MoA]
- manufacturer_name
- Daiichi Sankyo Inc.
- unii
- 32W99UE810
- spl_set_id
- e77d3400-56ad-11e3-949a-0800200c9a66
- upc
- 0365597201309
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_113241
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect37188
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_85976
- owl#annotatedSource
- t310978
- owl#someValuesFrom
- t3003836