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isavuconazonium

CHEBI:CHEBI_85978

Definition

An organic cation that is the cationic portion of isavuconazonium sulfate (a prodrug for isavuconazole, an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis).

Chemical Information

Molecular Formula
C35H35F2N8O5S
Molecular Mass
717.76400
Charge
+1
SMILES
CNCC(=O)OCc1cccnc1N(C)C(=O)OC(C)[n+]1cnn(C[C@@](O)([C@@H](C)c2nc(cs2)-c2ccc(cc2)C#N)c2cc(F)ccc2F)c1
InChI
InChI=1S/C35H35F2N8O5S/c1-22(33-42-30(18-51-33)25-9-7-24(15-38)8-10-25)35(48,28-14-27(36)11-12-29(28)37)19-45-21-44(20-41-45)23(2)50-34(47)43(4)32-26(6-5-13-40-32)17-49-31(46)16-39-3/h5-14,18,20-23,39,48H,16-17,19H2,1-4H3/q+1/t22-,23?,35+/m0/s1
InChIKey
RSWOJTICKMKTER-QXLBVTBOSA-N

Alternative Names

  • (2-{[(1-{1-[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1H-1,2,4-triazol-4-ium-4-yl}ethoxy)carbonyl](methyl)amino}pyridin-3-yl)methyl N-methylglycinate
  • BAL-8557
  • Isavuconazonium ion

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:85978
DRON_00010000
1608322
oboInOwl#hasDbXref
Drug_Central:4947

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:85978
active_ingredient_strength
.54 kg/kg
pharm_class
P-Glycoprotein Inhibitors [MoA]
active_ingredient_name
ISAVUCONAZONIUM SULFATE
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1608322
oboInOwl#hasDbXref
Drug_Central:4947
oboInOwl#id
CHEBI:85978
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
listing_expiration_date
20241231
route
ORAL
dosage_form
CAPSULE
generic_name
Isavuconazonium sulfate
brand_name
CRESEMBA
brand_name_base
CRESEMBA
product_ndc
73435-037
application_number
NDA207500
labeler_name
SwissCo Services AG
marketing_start_date
20151130
package_marketing_start_date
03-MAY-22
spl_id
0cfe1e2e-cca9-3bf0-e063-6394a90af559
package_ndc
73435-037-11
package_description
25 kg in 1 DRUM (73435-037-11)
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_77884
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113222
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect37194
owl#annotatedSource
t310720
owl#someValuesFrom
t3005425