avibactam
CHEBI:CHEBI_85984
Definition
A member of the class of azabicycloalkanes that is (2S,5R)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide in which the amino hydrogen at position 6 is replaced by a sulfooxy group. Used (in the form of its sodium salt) in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis.
Chemical Information
- Molecular Formula
- C7H11N3O6S
- Molecular Mass
- 265.24400
- Charge
- 0
- SMILES
- NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(O)(=O)=O
- InChI
- InChI=1S/C7H11N3O6S/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15/h4-5H,1-3H2,(H2,8,11)(H,13,14,15)/t4-,5+/m1/s1
- InChIKey
- NDCUAPJVLWFHHB-UHNVWZDZSA-N
Alternative Names
- (2S,5R)-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide
- NXL 104
- NXL104
Treatment Applications
-
pyelonephritisView Disease →
DOID:11400
Drug Classification
-
ureasView Class →
CHEBI:47857
-
monocarboxylic acid amideView Class →
CHEBI:29347
-
azabicycloalkaneView Class →
CHEBI:38295
-
hydroxylamine O-sulfonic acidView Class →
CHEBI:38025
-
t310182
-
t310189
-
t310286
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1603834
- oboInOwl#hasDbXref
- Wikipedia:Avibactam
- core#notation
- CHEBI:85984
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_107593
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect37224
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_85988
- owl#annotatedSource
- t310968
- owl#someValuesFrom
- t2999581
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1603834
- oboInOwl#hasDbXref
- Wikipedia:Avibactam
- oboInOwl#id
- CHEBI:85984
- core#notation
- CHEBI:85984
- listing_expiration_date
- 20251231
- dosage_form
- POWDER
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- active_ingredient_strength
- 1 kg/kg
- labeler_name
- Valdepharm
- marketing_start_date
- 20220622
- active_ingredient_name
- AVIBACTAM SODIUM
- package_marketing_start_date
- 22-JUN-22
- generic_name
- Avibactam Sodium
- product_ndc
- 24823-915
- spl_id
- 0e7f6f86-a0bd-b18a-e063-6394a90a8099
- package_ndc
- 24823-915-04
- package_description
- 4 kg in 1 DRUM (24823-915-04)
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35625
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_85988
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class