Pyrantel
CHEBI:CHEBI_8654
Definition
A carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoate)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'.
Chemical Information
- Molecular Formula
- C11H14N2S
- Molecular Mass
- 206.30700
- Charge
- 0
- SMILES
- CN1CCCN=C1\C=C\c1cccs1
- InChI
- InChI=1S/C11H14N2S/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h2,4-6,9H,3,7-8H2,1H3/b6-5+
- InChIKey
- YSAUAVHXTIETRK-AATRIKPKSA-N
Alternative Names
- 1-methyl-2-[(E)-2-(2-thienyl)vinyl]-1,4,5,6-tetrahydropyrimidine
- pirantel
- pyrantel
- pyrantelum
Drug Classification
-
thiophenesView Class →
CHEBI:26961
-
carboxamidineView Class →
CHEBI:35359
-
1,4,5,6-tetrahydropyrimidinesView Class →
CHEBI:78715
-
t314280
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 8984
- oboInOwl#hasDbXref
- Wikipedia:Pyrantel
- core#notation
- CHEBI:8654
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 8984
- oboInOwl#hasDbXref
- Wikipedia:Pyrantel
- oboInOwl#id
- CHEBI:8654
- dosage_form
- GRANULE
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- labeler_name
- REESE PHARMACEUTICAL CO.
- application_number
- part357B
- generic_name
- Pyrantel Tartrate Zeolex
- brand_name
- MebendamaX Pinworm
- brand_name_base
- MebendamaX
- product_ndc
- 51927-0235
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35444
- listing_expiration_date
- 20241231
- route
- ORAL
- marketing_start_date
- 20100519
- spl_id
- 0e9b301e-ab98-f6f9-e063-6394a90a877a
- package_ndc
- 51927-0235-0
- package_description
- 1 kg in 1 BOTTLE (51927-0235-0)
- core#notation
- CHEBI:8654
- rxcui
- 668538
- active_ingredient_strength
- 720.5 mg/.0015kg
- package_marketing_start_date
- 19-JUL-10
- manufacturer_name
- REESE PHARMACEUTICAL CO.
- active_ingredient_name
- PYRANTEL TARTRATE
- unii
- 81BK194Z5M
- spl_set_id
- fc225b5b-0ce8-4394-a643-39dbc674d7cd
- upc
- 0023513618210
- brand_name_suffix
- Medicine
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_7457
- owl#annotatedSource
- t314398
- owl#someValuesFrom
- t1058835