mycophenolate mofetil

CHEBI:CHEBI_8764

Definition

A carboxylic ester resulting from the formal condensation between the carboxylic acid group of mycophenolic acid and the hydroxy group of 2-(morpholin-4-yl)ethanol. In the liver, it is metabolised to mycophenolic acid, an immunosuppressant for which it is a prodrug. It is widely used to prevent tissue rejection following organ transplants as well as for the treatment of certain autoimmune diseases.

Chemical Information

Molecular Formula
C23H31NO7
Molecular Mass
433.49470
Charge
0
SMILES
COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(=O)OCCN1CCOCC1
InChI
InChI=1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+
InChIKey
RTGDFNSFWBGLEC-SYZQJQIISA-N

Alternative Names

  • MMF
  • 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate
  • 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
  • Cellcept
  • mycophenolic acid morpholinoethyl ester
  • RS 61443

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
68149
oboInOwl#hasDbXref
Wikipedia:Mycophenolate_mofetil
core#notation
CHEBI:8764

Additional References

Wikipedia:Mycophenolate_mofetil

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
INTRAVENOUS
package_ndc
67877-225-84
package_description
3 BLISTER PACK in 1 CARTON (67877-225-84) / 10 TABLET, FILM COATED in 1 BLISTER PACK
spl_id
e6858e74-bd78-48c3-9e8f-2a65498cd863
rxcui
616447
package_marketing_start_date
19970619
manufacturer_name
airis PHARMA Private Limited
unii
UXH81S8ZVB
spl_set_id
da02b428-42a4-4007-b0b7-695f2db010f2
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_168396
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
listing_expiration_date
20241231
labeler_name
airis PHARMA Private Limited
marketing_start_date
19970619
application_number
ANDA203859
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
68149
oboInOwl#hasDbXref
Wikipedia:Mycophenolate_mofetil
oboInOwl#id
CHEBI:8764
generic_name
Mycophenolate mofetil
brand_name
Mycophenolate mofetil
brand_name_base
Mycophenolate mofetil
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
product_ndc
67877-225
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_53746
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:8764
active_ingredient_strength
1 kg/kg
active_ingredient_name
MYCOPHENOLATE MOFETIL
pharm_class
Antimetabolite Immunosuppressant [EPC]
upc
0367457386812
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_8869
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect37584
owl#annotatedSource
t314420
owl#someValuesFrom
t2996294