Ramipril
CHEBI:CHEBI_8774
Definition
A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.
Chemical Information
- Molecular Formula
- C23H32N2O5
- Molecular Mass
- 416.51060
- Charge
- 0
- SMILES
- CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@H]2CCC[C@H]2C[C@H]1C(O)=O
- InChI
- InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
- InChIKey
- HDACQVRGBOVJII-JBDAPHQKSA-N
Alternative Names
- (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
- (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
- Altace (TN)
- ramipril
- Ramipril
- Ramiprilum
- Tritace
Drug Classification
-
ethyl esterView Class →
CHEBI:23990
-
dicarboxylic acid monoesterView Class →
CHEBI:36244
-
dipeptideView Class →
CHEBI:46761
-
azabicycloalkaneView Class →
CHEBI:38295
-
cyclopentapyrroleView Class →
CHEBI:38296
-
t313570
-
t313592
-
t314160
-
t314287
-
t314321
-
t314328
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 35296
- oboInOwl#hasDbXref
- Wikipedia:Ramipril
- core#notation
- CHEBI:8774
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 35296
- oboInOwl#hasDbXref
- Wikipedia:Ramipril
- oboInOwl#id
- CHEBI:8774
- core#notation
- CHEBI:8774
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_77496
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00723853
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_2746
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect37687
- owl#annotatedSource
- t314403
- owl#someValuesFrom
- t1008604