Discuss This Drug

CD437

CHEBI:CHEBI_88334

Definition

A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)gamma and induces cell cycle arrest and apoptosis in various cancer cells.

Chemical Information

Molecular Formula
C27H26O3
Molecular Mass
398.495
Charge
0
SMILES
C1C2(CC3CC(CC1C3)C2)C4=C(C=CC(=C4)C5=CC=C6C(=C5)C=CC(=C6)C(=O)O)O
InChI
InChI=1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
InChIKey
LDGIHZJOIQSHPB-UHFFFAOYSA-N

Alternative Names

  • 6-(3-adamantan-1-yl-4-hydroxyphenyl)naphthalene-2-carboxylic acid
  • 6-[4-hydroxy-3-(tricyclo[3.3.1.1(3,7)]dec-1-yl)phenyl]-2-naphthalenecarboxylic acid
  • 6-[4-hydroxy-3-(tricyclo[3.3.1.1(3,7)]dec-1-yl)phenyl]naphthalene-2-carboxylic acid
  • AHPN
  • Apoptosis Activator VI
  • Cd 437
  • CD-437

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Reaxys:7445028
core#notation
CHEBI:88334

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Reaxys:7445028
oboInOwl#id
CHEBI:88334
core#notation
CHEBI:88334
dosage_form
CREAM
route
TOPICAL
product_type
HUMAN OTC DRUG
marketing_category
OTC MONOGRAPH DRUG
active_ingredient_strength
5 g/100g
application_number
M016
active_ingredient_name
NIACINAMIDE
unii
25X51I8RD4
labeler_name
Yiwu Xinqian E Commerce Co Ltd
manufacturer_name
Yiwu Xinqian E Commerce Co Ltd
marketing_start_date
20241013
package_marketing_start_date
20241013
generic_name
C5 Super Boosteye Cream
brand_name
C5 Super Boosteye Cream
brand_name_base
C5 Super Boosteye Cream
product_ndc
84515-302
spl_id
2467e9b6-02b9-3e5e-e063-6294a90a49de
package_ndc
84515-302-01
package_description
15 g in 1 BOX (84515-302-01)
spl_set_id
2467e9b6-02b8-3e5e-e063-6294a90a49de
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_68495
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_31174
owl#someValuesFrom
t176461
owl#annotatedSource
t314399