Discuss This Drug

salmeterol

CHEBI:CHEBI_9011

Definition

A racemate consisting of equal parts of (R)- and (S)-salmeterol. It is a potent and selective beta2-adrenoceptor agonist (EC50 = 5.3 nM). Unlike other beta2 agonists, it binds to the exo-site domain of beta2 receptors, producing a slow onset of action and prolonged activation.

Chemical Information

Molecular Formula
C25H37NO4
Molecular Mass
415.56560
Charge
0

Alternative Names

  • (+-)-4-hydroxy-alpha(1)-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-alpha,alpha(1)-diol
  • (+-)-salmeterol
  • (RS)-4-hydroxy-alpha(1)-({[6-(4-phenylbutoxy)hexyl]amino}methyl)-1,3-benzenedimethanol
  • (RS)-salmeterol
  • salmeterol
  • Salmeterol
  • salmeterolum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:9011
oboInOwl#hasDbXref
Wikipedia:Salmeterol
DRON_00010000
36117

Additional References

Wikipedia:Salmeterol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:9011
brand_name_suffix
DISKUS
active_ingredient_name
SALMETEROL XINAFOATE
active_ingredient_strength
.4 kg/.4kg
unii
6EW8Q962A5
pharm_class
beta2-Adrenergic Agonist [EPC]
package_marketing_start_date
27-MAR-08
package_description
50 kg in 1 DRUM (14501-0045-2)
package_ndc
50909-4102-1
manufacturer_name
GlaxoSmithKline LLC
spl_set_id
12d9728e-6b5c-4aee-bfb0-745e542ed2e4
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Salmeterol
DRON_00010000
36117
oboInOwl#id
CHEBI:9011
generic_name
Salmeterol xinafoate
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
listing_expiration_date
20241231
route
RESPIRATORY (INHALATION)
dosage_form
POWDER, METERED
marketing_start_date
20080327
labeler_name
Amphastar Nanjing Pharmaceuticals
product_ndc
14501-0045
spl_id
0bec8942-ebec-5fb8-e063-6294a90a6ada
brand_name
SEREVENT DISKUS
brand_name_base
SEREVENT
application_number
NDA020692
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35522
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_64063
has_treatment
http://purl.obolibrary.org/obo/DOID_0080810
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect37984
owl#annotatedSource
t317814
owl#someValuesFrom
t3363076