Salsalate
CHEBI:CHEBI_9014
Definition
A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes.
Chemical Information
- Molecular Formula
- C14H10O5
- Molecular Mass
- 258.22620
- Charge
- 0
- SMILES
- OC(=O)c1ccccc1OC(=O)c1ccccc1O
- InChI
- InChI=1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17)
- InChIKey
- WVYADZUPLLSGPU-UHFFFAOYSA-N
Alternative Names
- 2-[(2-hydroxybenzoyl)oxy]benzoic acid
- 2-Carboxyphenyl salicylate
- Disalcid
- Disalicylic acid
- Disalicylsaeure
- O-Salicylcylsalicylsaeure
- o-Salicylsalicylic acid
- Salicylic acid bimolecular ester
- Salicyloxysalicylic acid
- Salicyloylsalicylic acid
- salicylsalicylic acid
- salsalate
- salsalato
- salsalatum
- Sasapyrin
- Sasapyrine
- Sasapyrinum
Drug Classification
-
phenolsView Class →
CHEBI:33853
-
benzoate esterView Class →
CHEBI:36054
-
benzoic acidsView Class →
CHEBI:22723
-
salicylatesView Class →
CHEBI:26596
-
t316593
-
t316725
-
t316872
-
t316985
-
t317368
-
t317396
-
t317405
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Salsalate
- DRON_00010000
- 36108
- core#notation
- CHEBI:9014
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Salsalate
- DRON_00010000
- 36108
- oboInOwl#id
- CHEBI:9014
- core#notation
- CHEBI:9014
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35625
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_16914
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0080273
- owl#annotatedSource
- t317871
- owl#someValuesFrom
- t2995572