Discuss This Drug

ACT-333679

CHEBI:CHEBI_90848

Definition

A member of the class of pyrazines that is {4-[(propan-2-yl)(pyrazin-2-yl)amino]butoxy}acetic acid carrying two additional phenyl substituents at positions 5 and 6 on the pyrazine ring. The active metabolite of selexipag, an orphan drug used for the treatment of pulmonary arterial hypertension.

Chemical Information

Molecular Formula
C25H29N3O3
Molecular Mass
419.517
Charge
0
SMILES
C1(=C(N=CC(=N1)N(CCCCOCC(O)=O)C(C)C)C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChI=1S/C25H29N3O3/c1-19(2)28(15-9-10-16-31-18-23(29)30)22-17-26-24(20-11-5-3-6-12-20)25(27-22)21-13-7-4-8-14-21/h3-8,11-14,17,19H,9-10,15-16,18H2,1-2H3,(H,29,30)
InChIKey
OJQMKCBWYCWFPU-UHFFFAOYSA-N

Alternative Names

  • {4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butoxy}acetic acid
  • ACT 333679
  • ACT333679
  • MRE 269
  • MRE-269
  • MRE269

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Reaxys:11140228
core#notation
CHEBI:90848

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_90844
owl#annotatedSource
t317886
owl#someValuesFrom
t317767
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Reaxys:11140228
oboInOwl#id
CHEBI:90848
core#notation
CHEBI:90848
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_49103
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class