Discuss This Drug

tipiracil

CHEBI:CHEBI_90879

Definition

A member of the class of pyrimidones that is uracil substituted by chloro and (2-iminopyrrolidin-1-yl)methyl groups at positions 5 and 6 respectively. Used (as the hydrochloride salt) in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer.

Chemical Information

Molecular Formula
C9H11ClN4O2
Molecular Mass
242.663
Charge
0
SMILES
C1(=C(C(NC(N1)=O)=O)Cl)CN2C(CCC2)=N
InChI
InChI=1S/C9H11ClN4O2/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11/h11H,1-4H2,(H2,12,13,15,16)
InChIKey
QQHMKNYGKVVGCZ-UHFFFAOYSA-N

Alternative Names

  • 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione
  • tipiracil

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:90879
DRON_00010000
1670304
oboInOwl#hasDbXref
Wikipedia:Tipiracil

Additional References

Wikipedia:Tipiracil

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:90879
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect38072
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_90880
owl#annotatedSource
t317891
owl#someValuesFrom
t2995442
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1670304
oboInOwl#hasDbXref
Wikipedia:Tipiracil
oboInOwl#id
CHEBI:90879
listing_expiration_date
20241231
dosage_form
POWDER
marketing_start_date
20190302
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
active_ingredient_strength
50 kg/50kg
package_marketing_start_date
02-MAR-19
labeler_name
NATCO PHARMA LIMITED
generic_name
Tipiracil hydrochloride
product_ndc
54893-0088
spl_id
0cca1fc2-30d8-15aa-e063-6394a90a595c
active_ingredient_name
TIPIRACIL HYDROCHLORIDE
package_ndc
54893-0088-4
package_description
20 kg in 1 DRUM (54893-0088-4)
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_90878
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_17568
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_90880