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tipiracil

CHEBI:CHEBI_90879

Definition

A member of the class of pyrimidones that is uracil substituted by chloro and (2-iminopyrrolidin-1-yl)methyl groups at positions 5 and 6 respectively. Used (as the hydrochloride salt) in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer.

Chemical Information

Molecular Formula
C9H11ClN4O2
Molecular Mass
242.663
Charge
0
SMILES
C1(=C(C(NC(N1)=O)=O)Cl)CN2C(CCC2)=N
InChI
InChI=1S/C9H11ClN4O2/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11/h11H,1-4H2,(H2,12,13,15,16)
InChIKey
QQHMKNYGKVVGCZ-UHFFFAOYSA-N

Alternative Names

  • 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione
  • tipiracil

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1670304
oboInOwl#hasDbXref
Wikipedia:Tipiracil
core#notation
CHEBI:90879

Additional References

Wikipedia:Tipiracil

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Additional Attributes

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chebi_ontology
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