uridine triacetate

CHEBI:CHEBI_90914

Definition

An acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity.

Chemical Information

Molecular Formula
C15H18N2O9
Molecular Mass
370.312
Charge
0
SMILES
[C@@H]1(N2C(NC(=O)C=C2)=O)O[C@H](COC(=O)C)[C@H]([C@H]1OC(=O)C)OC(=O)C
InChI
InChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1
InChIKey
AUFUWRKPQLGTGF-FMKGYKFTSA-N

Alternative Names

  • 2',3',5'-tri-O-acetyluridine
  • 2',3',5'-Triacetyluridine
  • PN 401
  • PN401
  • RG 2133
  • Tri-O-acetyluridine
  • Triacetyluridine
  • Uridine 2',3',5'-triacetate
  • uridine triacetate
  • Xuriden

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1665222
oboInOwl#hasDbXref
Reaxys:97869
core#notation
CHEBI:90914

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1665222
oboInOwl#hasDbXref
Reaxys:97869
oboInOwl#id
CHEBI:90914
core#notation
CHEBI:90914
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0050833
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_107200
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect38092
owl#annotatedSource
t317874
owl#someValuesFrom
t3006293