uridine triacetate
CHEBI:CHEBI_90914
Definition
An acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity.
Chemical Information
- Molecular Formula
- C15H18N2O9
- Molecular Mass
- 370.312
- Charge
- 0
- SMILES
- [C@@H]1(N2C(NC(=O)C=C2)=O)O[C@H](COC(=O)C)[C@H]([C@H]1OC(=O)C)OC(=O)C
- InChI
- InChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1
- InChIKey
- AUFUWRKPQLGTGF-FMKGYKFTSA-N
Alternative Names
- 2',3',5'-tri-O-acetyluridine
- 2',3',5'-Triacetyluridine
- PN 401
- PN401
- RG 2133
- Tri-O-acetyluridine
- Triacetyluridine
- Uridine 2',3',5'-triacetate
- uridine triacetate
- Xuriden
Treatment Applications
-
orotic aciduriaView Disease →
DOID:0050833
-
obsolete renal aminoaciduriaView Disease →
DOID:1061
Drug Classification
-
uridinesView Class →
CHEBI:27242
-
acetate esterView Class →
CHEBI:47622
-
t316736
-
t317750
-
t317788
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1665222
- oboInOwl#hasDbXref
- Reaxys:97869
- core#notation
- CHEBI:90914
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1665222
- oboInOwl#hasDbXref
- Reaxys:97869
- oboInOwl#id
- CHEBI:90914
- core#notation
- CHEBI:90914
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50266
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0050833
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_107200
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect38092
- owl#annotatedSource
- t317874
- owl#someValuesFrom
- t3006293