Discuss This Drug

aripiprazole lauroxil

CHEBI:CHEBI_90930

Definition

A dodecanoate ester obtained by formal condensation of the carboxy group of dodecanoic acid with the hydroxy group of 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-2-oxo-3,4-dihydroquinolin-1(2H)-yl]methanol. A prodrug for aripiprazole, it is used for treatment of schizophrenia.

Chemical Information

Molecular Formula
C36H51Cl2N3O4
Molecular Mass
660.715
Charge
0
SMILES
C=1(C=C2C(=CC1)CCC(N2COC(CCCCCCCCCCC)=O)=O)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl
InChI
InChI=1S/C36H51Cl2N3O4/c1-2-3-4-5-6-7-8-9-10-16-35(43)45-28-41-33-27-30(19-17-29(33)18-20-34(41)42)44-26-12-11-21-39-22-24-40(25-23-39)32-15-13-14-31(37)36(32)38/h13-15,17,19,27H,2-12,16,18,20-26,28H2,1H3
InChIKey
DDINXHAORAAYAD-UHFFFAOYSA-N

Alternative Names

  • [7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-2-oxo-3,4-dihydroquinolin-1(2H)-yl]methyl dodecanoate
  • ALKS 9070
  • ALKS 9072
  • Aristada
  • Dodecanoic acid, (7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butoxy)-3,4-dihydro-2-oxo-1(2H)-quinolinyl)methyl ester
  • RDC 3317
  • RDC-3317

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:90930
DRON_00010000
1673265
oboInOwl#hasDbXref
Reaxys:22857747

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
core#notation
CHEBI:90930
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1673265
generic_name
Aripiprazole Lauroxil
oboInOwl#hasDbXref
Reaxys:22857747
oboInOwl#id
CHEBI:90930
rxcui
1925264
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
INJECTION, SUSPENSION, EXTENDED RELEASE
route
INTRAMUSCULAR
marketing_start_date
20151005
active_ingredient_strength
675 mg/2.4mL
labeler_name
Alkermes, Inc.
active_ingredient_name
ARIPIPRAZOLE LAUROXIL
product_ndc
65757-500
package_marketing_start_date
29-JUN-18
spl_id
f0ecccf2-e3bb-46e6-9414-ae644245c6ea
package_ndc
65757-500-00
package_description
20 TRAY in 1 CARTON (65757-500-00) / 15 SYRINGE in 1 TRAY / 2.4 mL in 1 SYRINGE
manufacturer_name
Alkermes, Inc.
brand_name
ARISTADA
brand_name_base
ARISTADA
application_number
NDA207533
unii
B786J7A343
spl_set_id
17a8d11b-73b0-4833-a0b4-cf1ef85edefb
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37955
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect38119
owl#annotatedSource
t317831
owl#someValuesFrom
t3004155