cariprazine
CHEBI:CHEBI_90933
Definition
An N-alkylpiperazine that is N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea substituted at position 4 on the piperazine ring by a 2,3-dichlorophenyl group. Used (as the hydrochloride salt) for treatment of schizophrenia and bipolar disorder.
Chemical Information
- Molecular Formula
- C21H32Cl2N4O
- Molecular Mass
- 427.412
- Charge
- 0
- SMILES
- C1[C@H](CC[C@@H](C1)CCN2CCN(CC2)C=3C(=C(C=CC3)Cl)Cl)NC(N(C)C)=O
- InChI
- InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-
- InChIKey
- KPWSJANDNDDRMB-QAQDUYKDSA-N
Alternative Names
- cariprazine
- N'-(trans-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl)-N,N-dimethylurea
- RGH 188
- RGH-188
Drug Classification
-
ureasView Class →
CHEBI:47857
-
dichlorobenzeneView Class →
CHEBI:23697
-
DichlorobenzeneView Class →
CHEBI:23697
-
N-arylpiperazineView Class →
CHEBI:46848
-
N-alkylpiperazineView Class →
CHEBI:46845
-
t316598
-
t317297
-
t317513
-
t317702
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1667655
- oboInOwl#hasDbXref
- Wikipedia:Cariprazine
- core#notation
- CHEBI:90933
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1667655
- generic_name
- Cariprazine
- oboInOwl#hasDbXref
- Wikipedia:Cariprazine
- oboInOwl#id
- CHEBI:90933
- dosage_form
- CAPSULE, GELATIN COATED
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- labeler_name
- HOSTER LABS PRIVATE LIMITED
- listing_expiration_date
- 20241231
- route
- ORAL
- marketing_start_date
- 20150917
- product_ndc
- 61874-161
- spl_id
- 2319ab29-123d-a2a2-e063-6394a90a2609
- package_ndc
- 61874-161-00
- brand_name
- Vraylar
- brand_name_base
- Vraylar
- application_number
- NDA204370
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_51065
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_90934
- has_treatment
- http://purl.obolibrary.org/obo/DOID_11309
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect38131
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_90934
- owl#annotatedSource
- t317872
- owl#someValuesFrom
- t2988394
- core#notation
- CHEBI:90933
- rxcui
- 1741747
- manufacturer_name
- Allergan, Inc.
- active_ingredient_strength
- 4.5 mg/1
- nui
- N0000175430
- pharm_class_epc
- Atypical Antipsychotic [EPC]
- pharm_class
- Atypical Antipsychotic [EPC]
- package_marketing_start_date
- 17-JUL-15
- active_ingredient_name
- CARIPRAZINE HYDROCHLORIDE
- package_description
- 1 BAG in 1 DRUM (61874-161-00) / 65000 CAPSULE, GELATIN COATED in 1 BAG
- unii
- F6RJL8B278
- spl_set_id
- 4b5f7c65-aa2d-452a-b3db-bc85c06ff12f
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class