Discuss This Drug

cariprazine

CHEBI:CHEBI_90933

Definition

An N-alkylpiperazine that is N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea substituted at position 4 on the piperazine ring by a 2,3-dichlorophenyl group. Used (as the hydrochloride salt) for treatment of schizophrenia and bipolar disorder.

Chemical Information

Molecular Formula
C21H32Cl2N4O
Molecular Mass
427.412
Charge
0
SMILES
C1[C@H](CC[C@@H](C1)CCN2CCN(CC2)C=3C(=C(C=CC3)Cl)Cl)NC(N(C)C)=O
InChI
InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-
InChIKey
KPWSJANDNDDRMB-QAQDUYKDSA-N

Alternative Names

  • cariprazine
  • N'-(trans-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl)-N,N-dimethylurea
  • RGH 188
  • RGH-188

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
1667655
oboInOwl#hasDbXref
Wikipedia:Cariprazine
core#notation
CHEBI:90933

Additional References

Wikipedia:Cariprazine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1667655
generic_name
Cariprazine
oboInOwl#hasDbXref
Wikipedia:Cariprazine
oboInOwl#id
CHEBI:90933
dosage_form
CAPSULE, GELATIN COATED
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
labeler_name
HOSTER LABS PRIVATE LIMITED
listing_expiration_date
20241231
route
ORAL
marketing_start_date
20150917
product_ndc
61874-161
spl_id
2319ab29-123d-a2a2-e063-6394a90a2609
package_ndc
61874-161-00
brand_name
Vraylar
brand_name_base
Vraylar
application_number
NDA204370
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_51065
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_90934
has_treatment
http://purl.obolibrary.org/obo/DOID_11309
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect38131
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_90934
owl#annotatedSource
t317872
owl#someValuesFrom
t2988394
core#notation
CHEBI:90933
rxcui
1741747
manufacturer_name
Allergan, Inc.
active_ingredient_strength
4.5 mg/1
nui
N0000175430
pharm_class_epc
Atypical Antipsychotic [EPC]
pharm_class
Atypical Antipsychotic [EPC]
package_marketing_start_date
17-JUL-15
active_ingredient_name
CARIPRAZINE HYDROCHLORIDE
package_description
1 BAG in 1 DRUM (61874-161-00) / 65000 CAPSULE, GELATIN COATED in 1 BAG
unii
F6RJL8B278
spl_set_id
4b5f7c65-aa2d-452a-b3db-bc85c06ff12f
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class