Discuss This Drug

Sertraline

CHEBI:CHEBI_9123

Definition

A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder.

Chemical Information

Molecular Formula
C17H17Cl2N
Molecular Mass
306.23000
Charge
0
SMILES
[H][C@]1(CC[C@H](NC)c2ccccc12)c1ccc(Cl)c(Cl)c1
InChI
InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1
InChIKey
VGKDLMBJGBXTGI-SJCJKPOMSA-N

Alternative Names

  • (+)-sertraline
  • (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
  • (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
  • (1S,4S)-sertraline
  • cis-(+)-sertraline
  • CP 51974
  • sertralina
  • sertraline
  • Sertraline
  • sertralinum

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
36437
oboInOwl#hasDbXref
Wikipedia:Sertraline
core#notation
CHEBI:9123

Additional References

Wikipedia:Sertraline

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_ndc
65841-043
listing_expiration_date
20241231
spl_id
0cff4b55-42b7-46bb-98a3-b127c9626831
marketing_start_date
20240206
package_ndc
64220-224-09
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
SOLUTION, CONCENTRATE
labeler_name
NuCare pharmaceuticals,Inc.
application_number
ANDA076465
route
ORAL
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
36437
oboInOwl#hasDbXref
Wikipedia:Sertraline
oboInOwl#id
CHEBI:9123
generic_name
Sertraline Hydrochloride (Form V)
brand_name
sertraline HCl
brand_name_base
sertraline HCl
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50949
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_35008
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723854
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_64214
package_description
90 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (70518-1748-1)
package_marketing_start_date
06-MAR-96
rxcui
861066
manufacturer_name
NuCare pharmaceuticals,Inc.
unii
UTI8907Y6X
spl_set_id
f5679bb4-e709-0aee-e053-2995a90a5f42
core#notation
CHEBI:9123
upc
0382982043603
pharm_class
Serotonin Uptake Inhibitors [MoA]
active_ingredient_strength
20 mg/mL
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
active_ingredient_name
SERTRALINE
has_treatment
http://purl.obolibrary.org/obo/DOID_9240
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_105000
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect31015
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owl#someValuesFrom
t989966
owl#annotatedSource
t317884